INHBE - inhibin subunit beta E Gene

中文名称：抑制素亚基β E

种属: Homo sapiens

关于 INHBE

功能概要

该基因编码 TGF-β (转化生长因子-β) 蛋白质超家族的成员。编码的前原蛋白经过蛋白水解处理以生成抑制素 β 亚基。抑制素与调节许多细胞过程有关，包括细胞增殖、细胞凋亡、免疫反应和激素分泌。该基因可能在内质网应激条件下上调，并且该蛋白可能抑制胰腺和肝脏中的细胞增殖和生长。[RefSeq 提供，2016 年 9 月]

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. Inhibins have been implicated in regulating numerous cellular processes including cell proliferation, Apoptosis, immune response and hormone secretion. This gene may be upregulated under conditions of endoplasmic reticulum stress, and this protein may inhibit cellular proliferation and growth in pancreas and liver. [provided by RefSeq, Sep 2016]