1. Gene
  2. RIOK1 - RIO kinase 1 Gene

RIOK1 - RIO kinase 1 Gene

中文名称:RIO 激酶 1

种属: Homo sapiens

同用名: RIO1; AD034; RRP10; bA288G3.1

基因 ID: 83732 | 基因类型: protein coding

关于 RIOK1

Cytogenetic location: 6p24.3 Genomic coordinates (GRCh38): 6:7,389,808-7,418,037 (from NCBI)

This gene has 5 transcripts (splice variants), 198 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 12.9), bone marrow (RPKM 9.3) and 25 other tissues.

功能概要

由该基因编码的蛋白质与 pICln 竞争包含在蛋白质精氨酸甲基转移酶 5 复合物中。该复合物以底物为目标进行二甲基化。编码的蛋白质对于 40S 亚基成熟的最后步骤至关重要。[RefSeq 提供,2017 年 1 月]

The protein encoded by this gene competes with pICln for inclusion in the protein arginine methyltransferase 5 complex. This complex targets substrates for dimethylation. The encoded protein is essential for the last steps in the maturation of 40S subunits. [provided by RefSeq, Jan 2017]

RIOK1 基因产物(2)

mRNA Protein Name
NM_001348194.2 NP_001335123.1 serine/threonine-protein kinase RIO1 isoform 3
NM_031480.3 NP_113668.2 serine/threonine-protein kinase RIO1 isoform 1

RIOK1 蛋白结构

RIO1

RIO1: RIO1 family (193 - 380)

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  • 500
  • 568 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase RIO1

重组 RIOK1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76578 RIOK1 Protein, Human (sf9, His-GST) Q9BRS2 (M1-K568) ≥95%

关联疾病

疾病名称 别名
Cecum Carcinoma

Cecum Cancer

Caecum Carcinoma

Carcinoma Of Cecum

Cecal Cancer

Malignant Neoplasm Of Caecum

Malignant Tumor Of The Cecum

Cecum Adenocarcinoma

Cecal Adenocarcinoma

Adenocarcinoma Of Cecum

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RIOK1 RGD RGD:1306086
Macaca mulatta RIOK1 VGNC VGNC:76767
Mus musculus RIOK1 MGD MGI:1918590
Canis familiaris RIOK1 VGNC VGNC:54987
Bos taurus RIOK1 VGNC VGNC:50051
Felis catus RIOK1 VGNC VGNC:102503
Others RIOK1 NCBI