1. Gene
  2. Phip - pleckstrin homology domain interacting protein Gene

Phip - pleckstrin homology domain interacting protein Gene

种属: Mus musculus

同用名: Ndrp; Wdr11; 2810004D21Rik; 4632404O06Rik

基因 ID: 83946 | 基因类型: protein coding

关于 Phip

功能概要

Predicted to enable lysine-acetylated histone binding activity. Involved in several processes, including positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of mitotic nuclear division; and positive regulation of transcription, DNA-templated. Acts upstream of or within several processes, including Insulin Receptor signaling pathway; positive regulation of protein phosphorylation; and protein import into nucleus. Located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; female reproductive system; retina; and urinary system. Orthologous to human PHIP (pleckstrin homology domain interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Phip 基因产物(1)

mRNA Protein Name
NM_001081216.1 NP_001074685.1 PH-interacting protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11018022 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of cell population proliferation IGI
IGI: 通过遗传相互作用推断
17636024 MGI
acts upstream of fibroblast proliferation IMP
IMP: 通过突变表型推断
20816727 MGI
acts upstream of or within insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
11018022 MGI
involved in negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
17636024 MGI
acts upstream of peptidyl-serine phosphorylation IDA
IDA: 通过直接分析推断
17636024 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
17636024 MGI
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
17636024 MGI
acts upstream of or within positive regulation of fibroblast proliferation IMP
IMP: 通过突变表型推断
20816727 MGI
involved in positive regulation of insulin-like growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
17636024 MGI
involved in positive regulation of mitotic nuclear division IMP
IMP: 通过突变表型推断
17636024 MGI
acts upstream of or within positive regulation of peptidyl-serine phosphorylation IDA
IDA: 通过直接分析推断
17636024 MGI
acts upstream of or within positive regulation of peptidyl-threonine phosphorylation IDA
IDA: 通过直接分析推断
17636024 MGI
acts upstream of or within positive regulation of type B pancreatic cell proliferation IGI
IGI: 通过遗传相互作用推断
17636024 MGI
acts upstream of or within protein import into nucleus IMP
IMP: 通过突变表型推断
20816727 MGI
acts upstream of or within regulation of growth IMP
IMP: 通过突变表型推断
20816727 MGI
involved in regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
17636024 MGI
acts upstream of type B pancreatic cell proliferation IGI
IGI: 通过遗传相互作用推断
17636024 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
17636024 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

PH-interacting protein

IRS-1 PH domain-binding protein

WD repeat domain 11

WD repeat-containing protein 11

neuronal differentiation-related protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Phip NCBI NCBI:55023