TMPRSS13 - transmembrane serine protease 13 Gene

中文名称：跨膜丝氨酸蛋白酶 13

种属: Homo sapiens

同用名: MSP; MSPL; MSPS; TMPRSS11

关于 TMPRSS13

功能概要

该基因编码 II 型跨膜丝氨酸蛋白酶家族的成员。编码的蛋白质包含 II 型跨膜结构域、A 类受体结构域、清道夫受体富含半胱氨酸结构域和蛋白酶结构域。跨膜丝氨酸蛋白酶受蛋白酶抑制剂调节，已知在发育、稳态、感染和肿瘤发生中发挥作用。该蛋白通过蛋白水解切割和激活病毒包膜糖蛋白，促进病毒进入宿主细胞。[RefSeq 提供，2021 年 8 月]

This gene encodes a member of the type II transmembrane serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Transmembrane serine proteases are regulated by Protease Inhibitors and known to function in development, homeostasis, Infection, and tumorigenesis. This protein facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins. [provided by RefSeq, Aug 2021]