2. Gene
  3. C3ar1 - complement C3a receptor 1 Gene

C3ar1 - complement C3a receptor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 84007 | 基因类型: protein coding

关于 C3ar1

功能概要

Enables complement component C3a binding activity and complement component C3a receptor activity. Involved in several processes, including positive regulation of DNA biosynthetic process; positive regulation of cell population proliferation; and tolerance induction to nonself antigen. Located in plasma membrane. Used to study adult respiratory distress syndrome. Biomarker of asthma and lung disease. Human ortholog(s) of this gene implicated in asthma. Orthologous to human C3AR1 (complement C3a receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

C3ar1 基因产物(1)

mRNA Protein Name
NM_032060.2 NP_114449.2 C3a anaphylatoxin chemotactic receptor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables complement component C3a binding IDA
IDA: 通过直接分析推断
9464274 RGD
enables complement component C3a receptor activity IDA
IDA: 通过直接分析推断
9464274 RGD
enables complement component C3a receptor activity IPI
IPI: 通过物理相互作用推断
9464274 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of DNA biosynthetic process IMP
IMP: 通过突变表型推断
23713944 RGD
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
18635264 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
15292245 RGD
involved in positive regulation of glomerular mesangial cell proliferation IMP
IMP: 通过突变表型推断
23713944 RGD
involved in positive regulation of smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
22089112 RGD
involved in regulation of blood pressure IDA
IDA: 通过直接分析推断
19285573 RGD
involved in tolerance induction to nonself antigen IMP
IMP: 通过突变表型推断
12514742 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C3a anaphylatoxin chemotactic receptor

C3AR

C3a-R

complement component 3a receptor 1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1345A TLQP-21 TFA Agonist 99.90% 否
HY-RS21501 C3ar1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-P1345 TLQP-21 Agonist / 否
HY-RS01744 C3AR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28019 C3ar1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens C3ar1 NCBI NCBI:719
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