2. Gene
  3. Enpp2 - ectonucleotide pyrophosphatase/phosphodiesterase 2 Gene

Enpp2 - ectonucleotide pyrophosphatase/phosphodiesterase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 84050 | 基因类型: protein coding

关于 Enpp2

功能概要

Enables lysophospholipase activity; metal ion binding activity; and phosphoric diester hydrolase activity. Involved in several processes, including cellular response to estradiol stimulus; estrous cycle; and regulation of cell-substrate adhesion. Located in Golgi apparatus and extracellular space. Orthologous to human ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2). [provided by Alliance of Genome Resources, Apr 2022]

Enpp2 基因产物(1)

mRNA Protein Name
NM_057104.3 NP_476445.2 ectonucleotide pyrophosphatase/phosphodiesterase family member 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alkylglycerophosphoethanolamine phosphodiesterase activity IDA
IDA: 通过直接分析推断
24747415 RGD
enables calcium ion binding IDA
IDA: 通过直接分析推断
21240271 RGD
enables lysophospholipase activity IDA
IDA: 通过直接分析推断
12354767 RGD
enables phosphodiesterase I activity IMP
IMP: 通过突变表型推断
17307740 RGD
enables zinc ion binding IDA
IDA: 通过直接分析推断
21240271 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell chemotaxis IMP
IMP: 通过突变表型推断
17307740 RGD
involved in cellular response to cadmium ion IEP
IEP: 通过表达模式推断
24361405 RGD
involved in cellular response to estradiol stimulus IEP
IEP: 通过表达模式推断
18946176 RGD
involved in estrous cycle IEP
IEP: 通过表达模式推断
22122904 RGD
involved in negative regulation of cell-matrix adhesion IDA
IDA: 通过直接分析推断
12837632 RGD
involved in phosphatidylcholine catabolic process IDA
IDA: 通过直接分析推断
21240271 RGD
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
12119361 RGD
involved in positive regulation of focal adhesion assembly IDA
IDA: 通过直接分析推断
22139091 RGD
involved in positive regulation of oligodendrocyte differentiation IDA
IDA: 通过直接分析推断
22139091 RGD
involved in positive regulation of substrate adhesion-dependent cell spreading IDA
IDA: 通过直接分析推断
22139091 RGD
involved in response to polycyclic arene IEP
IEP: 通过表达模式推断
25490995 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
12837632 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ectonucleotide pyrophosphatase/phosphodiesterase family member 2

E-NPP 2

autotaxin

extracellular lysophospholipase D

lysoPLD

phosphodiesterase I/nucleotide pyrophosphatase 2 (autotaxin)

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-145344 ONO-8430506 Inhibitor 99.90% 否
HY-143582 ATX inhibitor 9 Inhibitor / 否
HY-146124 ATX inhibitor 21 Inhibitor / 否
HY-175478 Enpp-1-IN-27 / 否
HY-RS04388 ENPP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17381 Enpp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23836 Enpp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Enpp2 NCBI NCBI:5168
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