2. Gene
  3. SRPX - sushi repeat containing protein X-linked Gene

SRPX - sushi repeat containing protein X-linked Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 Sushi 重复序列的 X 连锁蛋白

种属: Homo sapiens

同用名: DRS; ETX1; SRPX1; HEL-S-83p

基因 ID: 8406 | 基因类型: protein coding

关于 SRPX

Cytogenetic location: Xp11.4 Genomic coordinates (GRCh38): X:38,149,339-38,220,871 (from NCBI)

This gene has 6 transcripts (splice variants), 190 orthologues and 39 paralogues. Broad expression in placenta (RPKM 49.3), fat (RPKM 34.8) and 19 other tissues.

功能概要

预测为细胞外基质结构成分。预计参与细胞粘附。预计在几个过程的上游或内部起作用，包括接触抑制中涉及的细胞增殖的负调节；吞噬溶酶体组装；在没有配体的情况下外在凋亡信号通路的正调节。含有胶原蛋白的细胞外基质的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be an extracellular matrix structural constituent. Predicted to be involved in cell adhesion. Predicted to act upstream of or within several processes, including negative regulation of cell proliferation involved in contact inhibition; phagolysosome assembly; and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. Part of collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

SRPX 基因产物(4)

mRNA Protein Name
NM_001170750.2 NP_001164221.1 sushi repeat-containing protein SRPX isoform 2 precursor
NM_001170751.2 NP_001164222.1 sushi repeat-containing protein SRPX isoform 3 precursor
NM_001170752.2 NP_001164223.1 sushi repeat-containing protein SRPX isoform 4 precursor
NM_006307.5 NP_006298.1 sushi repeat-containing protein SRPX isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20406461 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SRPX 蛋白结构

Sushi

Sushi: Sushi repeat (SCR repeat) (69 - 112)

Sushi

Sushi: Sushi repeat (SCR repeat) (135 - 174)

HYR

HYR: HYR domain (175 - 257)

Sushi

Sushi: Sushi repeat (SCR repeat) (262 - 317)

DUF4174

DUF4174: Domain of unknown function (DUF4174) (332 - 452)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 464 a.a.
蛋白主名 其他名称

sushi repeat-containing protein SRPX

epididymis secretory sperm binding protein Li 83p

关联疾病

疾病名称 别名
Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13782 SRPX Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS13783 SRPX2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17995 Srpx2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19642 Srpx Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24466 Srpx2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26135 Srpx Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SRPX RGD RGD:70950
Mus musculus SRPX MGD MGI:1858306
Bos taurus SRPX VGNC VGNC:50570
Others SRPX NCBI
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