2. Gene
  3. ZNF644 - zinc finger protein 644 Gene

ZNF644 - zinc finger protein 644 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：锌指蛋白 644

种属: Homo sapiens

同用名: NatF; MYP21; ZEP-2; BM-005

基因 ID: 84146 | 基因类型: protein coding

关于 ZNF644

Cytogenetic location: 1p22.2 Genomic coordinates (GRCh38): 1:90,915,304-91,022,035 (from NCBI)

This gene has 11 transcripts (splice variants), 242 orthologues, 51 paralogues and is associated with 1 phenotype. Ubiquitous expression in thyroid (RPKM 9.2), endometrium (RPKM 7.6) and 25 other tissues.

功能概要

该基因编码的蛋白质是一种锌指转录因子，可能在眼睛发育中发挥作用。该基因的缺陷与高度近视有关。已发现该基因编码两种不同亚型的三种转录变体。[RefSeq 提供，2011 年 8 月]

The protein encoded by this gene is a zinc finger transcription factor that may play a role in eye development. Defects in this gene have been associated with high myopia. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

ZNF644 基因产物(3)

mRNA Protein Name
NM_016620.4 NP_057704.2 zinc finger protein 644 isoform 2
NM_032186.5 NP_115562.3 zinc finger protein 644 isoform 2
NM_201269.3 NP_958357.1 zinc finger protein 644 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
25789554 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
25789554 GOA
enables transcription corepressor binding IPI
IPI: 通过物理相互作用推断
29628311 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZNF644 蛋白结构

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (410 - 432)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (448 - 470)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (965 - 985)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (1038 - 1060)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1327 a.a.
蛋白主名 其他名称

zinc finger protein 644

zinc finger motif enhancer binding protein 2

关联疾病

疾病名称 别名
Myopia 21, Autosomal Dominant

MYP21

Myopia, Type 21, Autosomal Dominant
Refractive Error

Refractive Errors
Myopia

Near-Sightedness

Short-Sightedness

Nearsightedness

Nearsighted

Near Vision

Close Sighted

Myopic

Short-Sighted

Near Sighted
Degenerative Myopia

Pathological Myopia

Myopia, Degenerative

Degenerative Progressive High Myopia

Progressive High Myopia

Progressive High Myopia
Anisometropia
Protoplasmic Astrocytoma

Protoplasmic Astrocytic Tumor

Astrocytoma Protoplasmic
Stickler Syndrome

Arthroophthalmopathy

Hereditary Arthro-Ophthalmo-Dystrophy

Hereditary Arthro-Ophthalmopathy

Stickler Dysplasia

Hereditary Progressive Arthroophthalmopathy

Stickler Syndrome, Type 1
Fundus Dystrophy

Retinal Dystrophy

Retinal Dystrophies

Dystrophy, Retinal
Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16162 ZNF644 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ZNF644 MGD MGI:1277212
Bos taurus ZNF644 VGNC VGNC:37320
Rattus norvegicus ZNF644 RGD RGD:1306805
Macaca mulatta ZNF644 VGNC VGNC:79789
Felis catus ZNF644 VGNC VGNC:67343
Canis familiaris ZNF644 VGNC VGNC:48784
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z