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  2. RPAIN - RPA interacting protein Gene

RPAIN - RPA interacting protein Gene

中文名称:RPA 相互作用蛋白

种属: Homo sapiens

同用名: RIP; HRIP

基因 ID: 84268 | 基因类型: protein coding

关于 RPAIN

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:5,420,182-5,432,877 (from NCBI)

This gene has 17 transcripts (splice variants) and 188 orthologues. Ubiquitous expression in lymph node (RPKM 8.1), testis (RPKM 8.0) and 25 other tissues.

功能概要

预测可启用金属离子结合活性。作用于多个过程的上游或内部,包括 DNA 代谢过程;蛋白质输入细胞核;和对紫外线的反应。位于 PML 体内;细胞质;和纤维中心。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including DNA metabolic process; protein import into nucleus; and response to UV. Located in PML body; cytoplasm; and fibrillar center. [provided by Alliance of Genome Resources, Apr 2022]

RPAIN 基因产物(5)

mRNA Protein Name
NM_001033002.4 NP_001028174.2 RPA-interacting protein isoform b
NM_001160243.2 NP_001153715.1 RPA-interacting protein isoform a
NM_001160244.2 NP_001153716.1 RPA-interacting protein isoform c
NM_001160246.2 NP_001153718.1 RPA-interacting protein isoform d
NM_001160266.2 NP_001153738.1 RPA-interacting protein isoform e
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within protein import into nucleus IDA
IDA: 通过直接分析推断
16135809 GOA
acts upstream of or within response to UV IDA
IDA: 通过直接分析推断
16135809 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in PML body IDA
IDA: 通过直接分析推断
16135809 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
16135809 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RPAIN 蛋白结构

RPA_interact_N

RPA_interact_N: Replication protein A interacting N-terminal (7 - 48)

RPA_interact_M

RPA_interact_M: Replication protein A interacting middle (60 - 127)

RPA_interact_C

RPA_interact_C: Replication protein A interacting C-terminal (136 - 218)

  • 0
  • 100
  • 200
  • 219 a.a.
蛋白主名 其他名称

RPA-interacting protein

RAP interaction protein

关联疾病

疾病名称 别名
Plantar Fasciitis

Fasciitis, Plantar

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RPAIN RGD RGD:1308492
Canis familiaris RPAIN VGNC VGNC:45705
Macaca mulatta RPAIN VGNC VGNC:76854
Bos taurus RPAIN VGNC VGNC:34097
Mus musculus RPAIN MGD MGI:1916973
Felis catus RPAIN VGNC VGNC:64727