1. Gene
  2. MAA - Col1a2 collagen type I alpha 2 chain Gene

MAA - Col1a2 collagen type I alpha 2 chain Gene

种属: Rattus norvegicus

基因 ID: 84352 | 基因类型: protein coding

关于 MAA

功能概要

Predicted to enable several functions, including identical protein binding activity; platelet-derived growth factor binding activity; and protease binding activity. Predicted to be an extracellular matrix structural constituent. Involved in cellular response to retinoic acid; cellular response to thyroid hormone stimulus; and response to norepinephrine. Predicted to be located in endoplasmic reticulum. Predicted to be part of Collagen type I trimer. Predicted to be active in extracellular matrix and extracellular space. Biomarker of hypothyroidism; muscular atrophy; pulmonary fibrosis; and ureteral obstruction. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome (multiple); heart valve disease; intracranial aneurysm; osteogenesis imperfecta (multiple); and osteoporosis. Orthologous to human COL1A2 (Collagen type I alpha 2 chain). [provided by Alliance of Genome Resources, Apr 2022]

MAA 基因产物(1)

mRNA Protein Name
NM_053356.2 NP_445808.2 collagen alpha-2(I) chain precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to aldehyde IEP
IEP: 通过表达模式推断
11295527 RGD
involved in cellular response to retinoic acid IEP
IEP: 通过表达模式推断
15234273 RGD
involved in cellular response to thyroid hormone stimulus IEP
IEP: 通过表达模式推断
1381294 RGD
involved in response to norepinephrine IEP
IEP: 通过表达模式推断
1951630 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

collagen alpha-2(I) chain

alpha-2 type I collagen

collagen, type I, alpha 2

procollagen, type I, alpha 2