1. Gene
  2. Asah1 - N-acylsphingosine amidohydrolase 1 Gene

Asah1 - N-acylsphingosine amidohydrolase 1 Gene

种属: Rattus norvegicus

同用名: Asah

基因 ID: 84431 | 基因类型: protein coding

关于 Asah1

功能概要

Predicted to enable N-acylsphingosine amidohydrolase activity; nuclear receptor binding activity; and transcription corepressor activity. Involved in lung development and response to organic substance. Predicted to be located in extracellular space; lysosome; and nucleus. Human ortholog(s) of this gene implicated in Farber lipogranulomatosis; sphingolipidosis; and spinal muscular atrophy with progressive myoclonic epilepsy. Orthologous to human ASAH1 (N-acylsphingosine amidohydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Asah1 基因产物(1)

mRNA Protein Name
NM_053407.3 NP_445859.2 acid ceramidase precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in lung development IDA
IDA: 通过直接分析推断
9160843 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

acid ceramidase

AC

ACDase

N-acylethanolamine hydrolase ASAH1

N-acylsphingosine amidohydrolase (acid ceramidase) 1

acid CDase

acylsphingosine deacylase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Asah1 NCBI NCBI:427