1. Gene
  2. DOC2B - double C2 domain beta Gene

DOC2B - double C2 domain beta Gene

中文名称:双 C2 域 beta

种属: Homo sapiens

同用名: DOC2BL

基因 ID: 8447 | 基因类型: protein coding

关于 DOC2B

Cytogenetic location: 17p13.3 Genomic coordinates (GRCh38): 17:142,789-181,650 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 199 orthologues and 31 paralogues. Ubiquitous expression in brain (RPKM 3.2), bone marrow (RPKM 2.6) and 22 other tissues.

功能概要

Double C2 蛋白至少有两种蛋白质亚型,即 alpha (DOC2A) 和 beta (DOC2B) ,它们包含两个 C2 样结构域。 DOC2A 和 DOC2B 由不同的基因编码;这些基因有时会与最初命名为 DOC-2 的不相关的 DAB2 基因相混淆。 DOC2B 无处不在,建议参与各种类型细胞中 CA (2+) 依赖性细胞内囊泡运输。[RefSeq 提供,2008 年 7 月]

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in CA(2+)-dependent intracellular vesicle trafficking in various types of cells. [provided by RefSeq, Jul 2008]

DOC2B 基因产物(1)

mRNA Protein Name
NM_003585.5 NP_003576.2 double C2-like domain-containing protein beta

DOC2B 蛋白结构

C2

C2: C2 domain (143 - 231)

C2

C2: C2 domain (283 - 307)

  • 0
  • 100
  • 200
  • 308 a.a.
蛋白主名 其他名称

double C2-like domain-containing protein beta

doc2-beta

关联疾病

疾病名称 别名
Cataract 8, Multiple Types

Ccv

Cataract, Congenital, Volkmann Type

CTRCT8

Cataract 8 Multiple Types

Cataract Congenital Volkmann Type

Cutaneous Collagenous Vasculopathy

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta DOC2B VGNC VGNC:71964
Rattus norvegicus DOC2B RGD RGD:620519
Bos taurus DOC2B VGNC VGNC:57140
Canis familiaris DOC2B VGNC VGNC:54939
Mus musculus DOC2B MGD MGI:1100497
Felis catus DOC2B VGNC VGNC:61569