2. Gene
  3. SLC4A4 - Slc4a4 solute carrier family 4 member 4 Gene

SLC4A4 - Slc4a4 solute carrier family 4 member 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: KNBC; NBC2; Nbc1; Nbc4; PNBC; HHNMC; HNBC1; SLC4A5

基因 ID: 84484 | 基因类型: protein coding

关于 SLC4A4

功能概要

Predicted to enable identical protein binding activity and sodium:bicarbonate symporter activity. Predicted to be involved in bicarbonate transport; regulation of intracellular pH; and sodium ion export across plasma membrane. Located in membrane. Used to study nephrogenic diabetes insipidus. Biomarker of hypertension. Human ortholog(s) of this gene implicated in renal tubular acidosis. Orthologous to human SLC4A4 (solute carrier family 4 member 4). [provided by Alliance of Genome Resources, Apr 2022]

SLC4A4 基因产物(1)

mRNA Protein Name
NM_053424.1 NP_445876.1 electrogenic sodium bicarbonate cotransporter 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sodium:bicarbonate symporter activity IDA
IDA: 通过直接分析推断
9486238 RGD
enables sodium:bicarbonate symporter activity IMP
IMP: 通过突变表型推断
12604466 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in metanephric proximal tubule development IEP
IEP: 通过表达模式推断
30645697 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
10069984 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

electrogenic sodium bicarbonate cotransporter 1

NBC-like protein

Na(+)/HCO3(-) cotransporter

Na+HCO3- cotransporter 4

sodium bicarbonate cotransporter

solute carrier family 4 (anion exchanger), member 4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13270 SLC4A4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19074 Slc4a4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25564 Slc4a4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens SLC4A4 NCBI NCBI:8671
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