2. Gene
  3. Xrcc1 - X-ray repair cross complementing 1 Gene

Xrcc1 - X-ray repair cross complementing 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 84495 | 基因类型: protein coding

关于 Xrcc1

功能概要

Predicted to enable enzyme binding activity and oxidized DNA binding activity. Predicted to contribute to 3' overhang single-stranded DNA endodeoxyribonuclease activity. Involved in several processes, including base-excision repair; response to hypoxia; and response to xenobiotic stimulus. Located in nucleus. Used to study in situ carcinoma. Biomarker of asphyxia neonatorum; transient cerebral ischemia; and visual epilepsy. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive spinocerebellar ataxia 26; carcinoma (multiple); hematologic Cancer (multiple); hepatitis A; and reproductive organ Cancer (multiple). Orthologous to human XRCC1 (X-ray repair cross complementing 1). [provided by Alliance of Genome Resources, Apr 2022]

Xrcc1 基因产物(1)

mRNA Protein Name
NM_053435.2 NP_445887.2 DNA repair protein XRCC1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17412650 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response IEP
IEP: 通过表达模式推断
11056294 RGD
involved in base-excision repair IDA
IDA: 通过直接分析推断
17412650 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
9763211 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11754170 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA repair protein XRCC1

X-ray repair complementing defective repair in Chinese hamster cells 1

X-ray repair cross-complementing protein 1

x-ray repair cross-complementing group 1 protein

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-171789 PARG-IN-7 Inhibitor / 否
HY-RS15896 XRCC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20130 Xrcc1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26634 Xrcc1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Xrcc1 NCBI NCBI:7515
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