2. Gene
  3. ATRN - attractin Gene

ATRN - attractin Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：吸引素

种属: Homo sapiens

同用名: MGCA; DPPT-L

基因 ID: 8455 | 基因类型: protein coding

关于 ATRN

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:3,471,018-3,651,118 (from NCBI)

This gene has 2 transcripts (splice variants), 209 orthologues and 27 paralogues. Ubiquitous expression in duodenum (RPKM 20.8), thyroid (RPKM 17.2) and 25 other tissues.

功能概要

该基因编码膜结合和分泌的蛋白质亚型。一种膜结合亚型与小鼠桃花心木蛋白 (一种参与控制肥胖的受体) 表现出序列相似性。分泌的亚型参与炎症反应期间的初始免疫细胞聚集，可能调节趋化因子的趋化活性。[RefSeq 提供，2016 年 4 月]

This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016]

ATRN 基因产物(4)

mRNA Protein Name
NM_001207047.3 NP_001193976.1 attractin isoform 4
NM_001323332.2 NP_001310261.1 attractin isoform 5 precursor
NM_139321.3 NP_647537.1 attractin isoform 1 preproprotein
NM_139322.4 NP_647538.1 attractin isoform 2 preproprotein
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17261078 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ATRN 蛋白结构

CUB

CUB: CUB domain (132 - 245)

Kelch_1

Kelch_1: Kelch motif (340 - 380)

Kelch_4

Kelch_4: Galactose oxidase, central domain (501 - 548)

Kelch_4

Kelch_4: Galactose oxidase, central domain (554 - 605)

Lectin_C

Lectin_C: Lectin C-type domain (806 - 920)

PSI

PSI: Plexin repeat (986 - 1061)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1429 a.a.
蛋白主名 其他名称

attractin

attractin-2

关联疾病

疾病名称 别名
Kidney Cortex Necrosis

Renal Cortical Necrosis
Seborrheic Dermatitis

Seborrhoeic Dermatitis

Seborrhea

Seborrhoeic Eczema

Skin Seborrheic

Dermatitis, Seborrheic
External Ear Disease

Diseases Of External Ear

Preauricular Cyst

Preauricular Sinus And Fistula

Preauricular Sinus Or Fistula
Otitis Externa

Swimmer'S Ear

Infective Otitis Externa

Acute Infective Otitis Externa
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01250 ATRN Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus ATRN VGNC VGNC:68790
Macaca mulatta ATRN VGNC VGNC:70194
Rattus norvegicus ATRN RGD RGD:69063
Canis familiaris ATRN VGNC VGNC:38295
Bos taurus ATRN VGNC VGNC:26335
Mus musculus ATRN MGD MGI:1341628
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