2. Gene
  3. Ncoa3 - nuclear receptor coactivator 3 Gene

Ncoa3 - nuclear receptor coactivator 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Aib1; Tram-1

基因 ID: 84584 | 基因类型: protein coding

关于 Ncoa3

功能概要

Enables several functions, including nuclear receptor binding activity; nuclear receptor coactivator activity; and peroxisome proliferator activated receptor binding activity. Involved in several processes, including male gonad development; positive regulation of intracellular Estrogen receptor signaling pathway; and regulation of transcription, DNA-templated. Located in Golgi apparatus; nucleus; and perinuclear region of cytoplasm. Used to study breast Cancer. Human ortholog(s) of this gene implicated in obesity. Orthologous to human NCOA3 (nuclear receptor coactivator 3). [provided by Alliance of Genome Resources, Apr 2022]

Ncoa3 基因产物(1)

mRNA Protein Name
NM_053454.1 NP_445906.1 nuclear receptor coactivator 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15166231 RGD
enables nuclear androgen receptor binding IPI
IPI: 通过物理相互作用推断
17223690 RGD
enables nuclear estrogen receptor binding IPI
IPI: 通过物理相互作用推断
11818503 RGD
enables nuclear receptor coactivator activity IDA
IDA: 通过直接分析推断
11713241 RGD
enables peroxisome proliferator activated receptor binding IPI
IPI: 通过物理相互作用推断
20132223 RGD
enables protein-containing complex binding IMP
IMP: 通过突变表型推断
20132223 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cerebellum development IEP
IEP: 通过表达模式推断
10803578 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
16189181 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
21454665 RGD
involved in positive regulation of DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
11713241 RGD
involved in positive regulation of cell growth IMP
IMP: 通过突变表型推断
21454665 RGD
involved in positive regulation of intracellular estrogen receptor signaling pathway IDA
IDA: 通过直接分析推断
11713241 RGD
involved in positive regulation of intracellular steroid hormone receptor signaling pathway IMP
IMP: 通过突变表型推断
16179382 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17481888 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
16179382 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor coactivator 3

AIB-1

NCoA-3

amplified in breast cancer-1 protein homolog

thyroid hormone receptor activator molecule 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09091 NCOA3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20451 Ncoa3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26960 Ncoa3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ncoa3 NCBI NCBI:8202
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