2. Gene
  3. BCAS1 - brain enriched myelin associated protein 1 Gene

BCAS1 - brain enriched myelin associated protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：脑富集髓鞘相关蛋白 1

种属: Homo sapiens

同用名: AIBC1; NABC1; PMES-2

基因 ID: 8537 | 基因类型: protein coding

关于 BCAS1

Cytogenetic location: 20q13.2 Genomic coordinates (GRCh38): 20:53,943,541-54,070,594 (from NCBI)

This gene has 11 transcripts (splice variants) and 125 orthologues. Biased expression in stomach (RPKM 58.5), colon (RPKM 41.1) and 7 other tissues.

功能概要

该基因位于 20q13 的一个区域，该区域在多种肿瘤类型中被扩增，并与更具侵袭性的肿瘤表型相关。在从该区域鉴定的基因中，发现它在 20q13.2 的三个扩增的乳腺癌细胞系和一个未扩增的乳腺肿瘤中高表达。然而，该基因不在最大扩增的共同区域，并且在该区域高度扩增的乳腺癌细胞系 MCF7 中未检测到其表达。虽然表达不一致，但该基因是候选致癌基因。[RefSeq 提供，2016 年 4 月]

This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast Cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast Cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Apr 2016]

BCAS1 基因产物(7)

mRNA Protein Name
NM_001316361.3 NP_001303290.1 breast carcinoma-amplified sequence 1 isoform 2
NM_001323347.2 NP_001310276.1 breast carcinoma-amplified sequence 1 isoform 2
NM_001366295.2 NP_001353224.1 breast carcinoma-amplified sequence 1 isoform 3
NM_001366296.2 NP_001353225.1 breast carcinoma-amplified sequence 1 isoform 4
NM_001366297.2 NP_001353226.1 breast carcinoma-amplified sequence 1 isoform 5
NM_001366298.2 NP_001353227.1 breast carcinoma-amplified sequence 1 isoform 6
NM_003657.4 NP_003648.2 breast carcinoma-amplified sequence 1 isoform 1
蛋白主名 其他名称

breast carcinoma-amplified sequence 1

amplified and overexpressed in breast cancer

关联疾病

疾病名称 别名
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16993 OICR-9429 99.71% 否
HY-RS01399 BCAS1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus BCAS1 MGD MGI:1924210
Macaca mulatta BCAS1 VGNC VGNC:98871
Rattus norvegicus BCAS1 RGD RGD:628644
Felis catus BCAS1 VGNC VGNC:98869
Canis familiaris BCAS1 VGNC VGNC:98867
Bos taurus BCAS1 VGNC VGNC:98868
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