2. Gene
  3. Gata3 - GATA binding protein 3 Gene

Gata3 - GATA binding protein 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 85471 | 基因类型: protein coding

关于 Gata3

功能概要

Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in several processes, including cochlea development; response to gamma radiation; and type IV hypersensitivity. Located in nucleus. Biomarker of asthma. Human ortholog(s) of this gene implicated in hypoparathyroidism; hypoparathyroidism-deafness-renal disease syndrome; nephrosis; and sensorineural hearing loss. Orthologous to human GATA3 (GATA binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Gata3 基因产物(1)

mRNA Protein Name
NM_133293.2 NP_579827.1 trans-acting T-cell-specific transcription factor GATA-3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
9125153 RGD
enables histone methyltransferase binding IPI
IPI: 通过物理相互作用推断
34694864 RGD
enables sequence-specific DNA binding IMP
IMP: 通过突变表型推断
9125153 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cochlea development IEP
IEP: 通过表达模式推断
20006695 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9125153 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
19428696 RGD
involved in response to gamma radiation IEP
IEP: 通过表达模式推断
19084914 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
19428696 RGD
involved in type IV hypersensitivity IEP
IEP: 通过表达模式推断
16336837 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

trans-acting T-cell-specific transcription factor GATA-3

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-138113 Pyrrothiogatain Inhibitor 98.61% 否
HY-N0407 Picroside I Inhibitor 99.48% 否
HY-RS05291 GATA3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174675 Human GATA3 mRNA / 否
HY-RS17910 Gata3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24379 Gata3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gata3 NCBI NCBI:2625
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