1. Gene
  2. OR6A2 - olfactory receptor family 6 subfamily A member 2 Gene

OR6A2 - olfactory receptor family 6 subfamily A member 2 Gene

中文名称:嗅觉受体家族 6 亚科 A 成员 2

种属: Homo sapiens

同用名: I7; OR6A1; OR6A2P; OR11-55

基因 ID: 8590 | 基因类型: protein coding

关于 OR6A2

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:6,791,736-6,799,689 (from NCBI)

This gene has 1 transcript (splice variant), 160 orthologues and 92 paralogues.

功能概要

嗅觉受体与鼻子中的气味分子相互作用,引发神经元反应,从而触发对气味的感知。嗅觉受体蛋白是来自单个编码外显子基因的 G 蛋白偶联受体 (GPCR) 大家族的成员。嗅觉受体与许多神经递质和激素受体共享一个 7 跨膜结构域,负责气味信号的识别和 G 蛋白介导的转导。嗅觉受体基因家族是基因组中最大的。分配给该生物体的嗅觉受体基因和蛋白质的命名法独立于其他生物体。[RefSeq 提供,2008 年 7 月]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The Olfactory Receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The Olfactory Receptor gene family is the largest in the genome. The nomenclature assigned to the Olfactory Receptor genes and proteins for this organism is independent of Other organisms. [provided by RefSeq, Jul 2008]

OR6A2 基因产物(1)

mRNA Protein Name
NM_003696.3 NP_003687.2 olfactory receptor 6A2

OR6A2 蛋白结构

7tm_4

7tm_4: Olfactory receptor (144 - 288)

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  • 327 a.a.
蛋白主名 其他名称

olfactory receptor 6A2

hI7 olfactory receptor

关联疾病

疾病名称 别名
Retinitis Pigmentosa 24

RP24

Retinitis Pigmentosa-24

Retinitis Pigmentosa 3

RP3

Retinitis Pigmentosa 15

Rp15

Choroidoretinal Degeneration With Retinal Reflex In Heterozygous Women

Cone-Rod Degeneration, X-Linked

Retinitis Pigmentosa Type 15

X-Linked Cone-Rod Degeneration

X-Linked Retinitis Pigmentosa 3

Xlrp3

Xlrp-3

Retinitis Pigmentosa-3

Retinitis Pigmentosa, Type 3

Placental Choriocarcinoma

Choriocarcinoma Of The Placenta

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus OR6A2 MGD MGI:97432
Rattus norvegicus OR6A2 RGD RGD:68340
Canis familiaris OR6A2 VGNC VGNC:96976
Bos taurus OR6A2 VGNC VGNC:101670