2. Gene
  3. Sfrp4 - secreted frizzled-related protein 4 Gene

Sfrp4 - secreted frizzled-related protein 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 89803 | 基因类型: protein coding

关于 Sfrp4

功能概要

Enables Wnt-protein binding activity. Involved in several processes, including decidualization; mammary gland involution; and negative regulation of signal transduction. Located in cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in metaphyseal dysplasia. Orthologous to human SFRP4 (secreted Frizzled related protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Sfrp4 基因产物(1)

mRNA Protein Name
NM_053544.2 NP_445996.2 secreted frizzled-related protein 4 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Wnt-protein binding IPI
IPI: 通过物理相互作用推断
18567805 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in decidualization IEP
IEP: 通过表达模式推断
12063187 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
16540541 RGD
involved in mammary gland involution IEP
IEP: 通过表达模式推断
9409757 RGD
involved in negative regulation of JNK cascade IDA
IDA: 通过直接分析推断
18567805 RGD
involved in negative regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
12952927 RGD
involved in negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
18567805 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
12063187 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
16540541 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
12960062 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
12960062 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

secreted frizzled-related protein 4

DDC-4 protein

FRP

frizzled related protein

sFRP-4

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12776 SFRP4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17510 Sfrp4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23967 Sfrp4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sfrp4 NCBI NCBI:6424
Mus musculus Sfrp4 NCBI NCBI:20379
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