2. Gene
  3. SHF - Src homology 2 domain containing F Gene

SHF - Src homology 2 domain containing F Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 Src 同源 2 结构域 F

种属: Homo sapiens

基因 ID: 90525 | 基因类型: protein coding

关于 SHF

Cytogenetic location: 15q21.1 Genomic coordinates (GRCh38): 15:45,167,214-45,201,116 (from NCBI)

This gene has 12 transcripts (splice variants), 205 orthologues and 3 paralogues. Ubiquitous expression in adrenal (RPKM 4.2), ovary (RPKM 4.0) and 23 other tissues.

功能概要

预测启用磷酸酪氨酸残基结合活性。预测参与细胞凋亡过程。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable phosphotyrosine residue binding activity. Predicted to be involved in apoptotic process. [provided by Alliance of Genome Resources, Apr 2022]

SHF 基因产物(17)

mRNA Protein Name
NM_001301168.2 NP_001288097.2 SH2 domain-containing adapter protein F isoform a
NM_001301169.2 NP_001288098.2 SH2 domain-containing adapter protein F isoform c
NM_001301170.2 NP_001288099.2 SH2 domain-containing adapter protein F isoform d
NM_001301171.2 NP_001288100.2 SH2 domain-containing adapter protein F isoform e
NM_001394037.1 NP_001380966.1 SH2 domain-containing adapter protein F isoform f
NM_001394038.1 NP_001380967.1 SH2 domain-containing adapter protein F isoform g
NM_001394039.1 NP_001380968.1 SH2 domain-containing adapter protein F isoform h
NM_001394040.1 NP_001380969.1 SH2 domain-containing adapter protein F isoform i
NM_001394041.1 NP_001380970.1 SH2 domain-containing adapter protein F isoform j
NM_001394042.1 NP_001380971.1 SH2 domain-containing adapter protein F isoform k
NM_001394043.1 NP_001380972.1 SH2 domain-containing adapter protein F isoform l
NM_001394044.1 NP_001380973.1 SH2 domain-containing adapter protein F isoform m
NM_001394045.1 NP_001380974.1 SH2 domain-containing adapter protein F isoform n
NM_001394046.1 NP_001380975.1 SH2 domain-containing adapter protein F isoform o
NM_001394047.1 NP_001380976.1 SH2 domain-containing adapter protein F isoform p
NM_001394048.1 NP_001380977.1 SH2 domain-containing adapter protein F isoform q
NM_138356.3 NP_612365.3 SH2 domain-containing adapter protein F isoform b

SHF 蛋白结构

SH2

SH2: SH2 domain (323 - 399)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 423 a.a.
蛋白主名 其他名称

SH2 domain-containing adapter protein F

CTD-2651B20.7

关联疾病

疾病名称 别名
Enamel Erosion
Tooth Erosion

Generalized Erosion

Localized Erosion

Generalized Erosions

Erosion, Localized
Pyosalpinx

Pyosalpingitis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10536 Temporin SHF Inhibitor / 否
HY-RS12863 SHF Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus SHF VGNC VGNC:34596
Rattus norvegicus SHF RGD RGD:1562705
Mus musculus SHF MGD MGI:3613669
Canis familiaris SHF VGNC VGNC:59130
Felis catus SHF VGNC VGNC:80846
Macaca mulatta SHF VGNC VGNC:99239
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