TBL1Y - transducin beta like 1 Y-linked Gene

中文名称：转导蛋白 β 样 1 Y 连锁

种属: Homo sapiens

同用名: TBL1; DFNY2

关于 TBL1Y

功能概要

该基因编码的蛋白质与含有 WD40 重复序列的蛋白质家族成员具有序列相似性。 WD40 组是一大类蛋白质，似乎具有调节功能。据信，WD40 重复序列介导蛋白质-蛋白质相互作用，该家族成员参与信号转导、RNA 加工、基因调控、囊泡运输、细胞骨架组装，并可能在细胞型分化的控制中发挥作用。该基因与 TBL1X 基因在核苷酸序列和蛋白质序列上高度相似，但 TBL1X 基因位于 X 染色体，该基因位于 Y 染色体。该基因具有编码相同蛋白质的三个可变剪接转录本变异体。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]