2. Gene
  3. ANGEL2 - angel homolog 2 Gene

ANGEL2 - angel homolog 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：天使同系物 2

种属: Homo sapiens

同用名: Ccr4d; KIAA0759L

基因 ID: 90806 | 基因类型: protein coding

关于 ANGEL2

Cytogenetic location: 1q32.3 Genomic coordinates (GRCh38): 1:212,992,182-213,015,867 (from NCBI)

This gene has 8 transcripts (splice variants), 208 orthologues and 5 paralogues. Ubiquitous expression in brain (RPKM 5.6), lymph node (RPKM 5.1) and 25 other tissues.

功能概要

启用 mRNA 3'-UTR 结合活性。参与 3'-UTR 介导的 mRNA 稳定和有丝分裂细胞周期的负调节。位于 Cajal 体和细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables mRNA 3'-UTR binding activity. Involved in 3'-UTR-mediated mRNA stabilization and negative regulation of mitotic cell cycle. Located in Cajal body and cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ANGEL2 基因产物(5)

mRNA Protein Name
NM_001300753.2 NP_001287682.1 protein angel homolog 2 isoform b
NM_001300755.2 NP_001287684.1 protein angel homolog 2 isoform b
NM_001300757.2 NP_001287686.1 protein angel homolog 2 isoform c
NM_001300758.2 NP_001287687.1 protein angel homolog 2 isoform c
NM_144567.5 NP_653168.2 protein angel homolog 2 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA 3'-UTR binding IDA
IDA: 通过直接分析推断
22547059 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 3'-UTR-mediated mRNA stabilization IMP
IMP: 通过突变表型推断
22547059 GOA
involved in negative regulation of mitotic cell cycle IMP
IMP: 通过突变表型推断
22547059 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Cajal body IDA
IDA: 通过直接分析推断
17178830 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
17178830 GOA
is active in mitochondrial matrix IDA
IDA: 通过直接分析推断
36180430 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ANGEL2 蛋白结构

Exo_endo_phos

Exo_endo_phos: Endonuclease/Exonuclease/phosphatase family (170 - 533)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 544 a.a.
蛋白主名 其他名称

protein angel homolog 2

关联疾病

疾病名称 别名
Pontocerebellar Hypoplasia, Type 7

Pontocerebellar Hypoplasia Type 7

PCH7

Pontocerebellar Hypoplasia-46,Xy Disorder Of Sex Development Syndrome

Pontocerebellar Hypoplasia 7

Hypoplasia, Pontocerebellar, Type 7
Rheumatoid Arthritis Interstitial Lung Disease

Rheumatoid Lung
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00686 ANGEL2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ANGEL2 VGNC VGNC:37853
Macaca mulatta ANGEL2 VGNC VGNC:69737
Felis catus ANGEL2 VGNC VGNC:59779
Mus musculus ANGEL2 MGD MGI:1196310
Bos taurus ANGEL2 VGNC VGNC:25887
Rattus norvegicus ANGEL2 RGD RGD:1305056
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