2. Gene
  3. ESAM - endothelial cell adhesion molecule Gene

ESAM - endothelial cell adhesion molecule Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：内皮细胞粘附分子

种属: Homo sapiens

同用名: W117m

基因 ID: 90952 | 基因类型: protein coding

关于 ESAM

Cytogenetic location: 11q24.2 Genomic coordinates (GRCh38): 11:124,753,126-124,762,290 (from NCBI)

This gene has 6 transcripts (splice variants), 292 orthologues and 14 paralogues. Broad expression in placenta (RPKM 71.1), thyroid (RPKM 67.5) and 21 other tissues.

功能概要

启用细胞间粘附介质活性。参与多个过程，包括双细胞紧密连接组装；细胞间粘附；和肌动蛋白细胞骨架组织的调节。位于细胞间连接处和质膜上。部分含蛋白质复合物。 [由基因组资源联盟提供，2022 年 4 月]

Enables cell-cell adhesion mediator activity. Involved in several processes, including bicellular tight junction assembly; cell-cell adhesion; and regulation of actin Cytoskeleton organization. Located in cell-cell junction and plasma membrane. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

ESAM 基因产物(1)

mRNA Protein Name
NM_138961.3 NP_620411.2 endothelial cell-selective adhesion molecule precursor

ESAM 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (36 - 139)

Ig_2

Ig_2: Immunoglobulin domain (163 - 240)

  • 0
  • 100
  • 200
  • 300
  • 390 a.a.
蛋白主名 其他名称

endothelial cell-selective adhesion molecule

2310008D05Rik

重组 ESAM 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70889 ESAM Protein, Human (HEK293, His) Q96AP7 (Q30-A247 ) ≥95%

关联疾病

疾病名称 别名
Aqueous Misdirection
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04520 ESAM Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ESAM VGNC VGNC:53356
Macaca mulatta ESAM VGNC VGNC:72290
Rattus norvegicus ESAM RGD RGD:1303286
Felis catus ESAM VGNC VGNC:102878
Mus musculus ESAM MGD MGI:1916774
Bos taurus ESAM VGNC VGNC:50042
Others ESAM NCBI
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