2. Gene
  3. SLC16A4 - solute carrier family 16 member 4 Gene

SLC16A4 - solute carrier family 16 member 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 16 成员 4

种属: Homo sapiens

同用名: MCT4; MCT5

基因 ID: 9122 | 基因类型: protein coding

关于 SLC16A4

Cytogenetic location: 1p13.3 Genomic coordinates (GRCh38): 1:110,362,857-110,391,026 (from NCBI)

This gene has 10 transcripts (splice variants), 244 orthologues and 13 paralogues. Biased expression in kidney (RPKM 44.3), placenta (RPKM 12.3) and 10 other tissues.

功能概要

预计可启用单羧酸跨膜转运蛋白活性。预计参与单羧酸运输。预测位于膜中。预计是质膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC16A4 基因产物(6)

mRNA Protein Name
NM_001201546.2 NP_001188475.1 monocarboxylate transporter 5 isoform 2
NM_001201547.2 NP_001188476.1 monocarboxylate transporter 5 isoform 3
NM_001201548.2 NP_001188477.1 monocarboxylate transporter 5 isoform 4
NM_001201549.2 NP_001188478.1 monocarboxylate transporter 5 isoform 5
NM_001319220.2 NP_001306149.1 monocarboxylate transporter 5 isoform 6
NM_004696.3 NP_004687.1 monocarboxylate transporter 5 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC16A4 蛋白结构

MFS_1

MFS_1: Major Facilitator Superfamily (28 - 360)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 487 a.a.
蛋白主名 其他名称

monocarboxylate transporter 5

MCT 4

关联疾病

疾病名称 别名
Pancreatic Cancer

Pancreatic Carcinoma

Carcinoma Of Pancreas

Familial Pancreatic Carcinoma

Pancreatic Neoplasm

Pancreatic Carcinoma, Familial

Malignant Neoplasm Of Pancreas

Pancreatic Acinar Carcinoma

Pancreatic Tumor

Familial Pancreatic Cancer

Neoplasm Of The Pancreas

Cancer Of The Pancreas

Pancreatic Carcinoma, Somatic

Pancreatic Cancer, Somatic

Ca Body Of Pancreas

Ca Head Of Pancreas

Ca Tail Of Pancreas

Malignant Neoplasm Of Body Of Pancreas

Malignant Neoplasm Of Head Of Pancreas

Malignant Neoplasm Of Tail Of Pancreas

Pancreas Neoplasm

Exocrine Cancer

Exocrine Pancreas Carcinoma

Hereditary Pancreatic Cancer

Hereditary Pancreatic Carcinoma

PNCA

Pancreatic Cancer, Susceptibility To

Carcinoma Of Head Of Pancreas

Pancreatic Neoplasms

Pancreatic Tumors

Cancer, Pancreatic

Cancer Of Pancreas

Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Pharynx Squamous Cell Carcinoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13026 SLC16A4 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus SLC16A4 VGNC VGNC:65211
Mus musculus SLC16A4 MGD MGI:2385183
Bos taurus SLC16A4 VGNC VGNC:34690
Rattus norvegicus SLC16A4 RGD RGD:1359655
Canis familiaris SLC16A4 VGNC VGNC:46243
Macaca mulatta SLC16A4 VGNC VGNC:77398
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