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  2. TMEM259 - transmembrane protein 259 Gene

TMEM259 - transmembrane protein 259 Gene

中文名称:跨膜蛋白 259

种属: Homo sapiens

同用名: MBRL; ASBABP1; C19orf6; R32184_3; MEMBRALIN

基因 ID: 91304 | 基因类型: protein coding

关于 TMEM259

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,009,653-1,021,123 (from NCBI)

This gene has 12 transcripts (splice variants), 190 orthologues and 1 paralogue. Ubiquitous expression in spleen (RPKM 49.2), fat (RPKM 38.4) and 25 other tissues.

功能概要

预计参与 ERAD 通路的正调控和对内质网应激的反应。预测位于内质网膜。预计是膜的组成部分。预计在内质网中有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in positive regulation of ERAD pathway and response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

TMEM259 基因产物(2)

mRNA Protein Name
NM_001033026.2 NP_001028198.1 membralin isoform 1
NM_033420.4 NP_219488.1 membralin isoform 2

TMEM259 蛋白结构

Membralin

Membralin: Tumour-associated protein (34 - 402)

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  • 620 a.a.
蛋白主名 其他名称

membralin

aspecific BCL2 ARE-binding protein 1

直系同源

种属 基因名 来源 基因 ID
Mus musculus TMEM259 MGD MGI:2177957
Rattus norvegicus TMEM259 RGD RGD:1311136
Canis familiaris TMEM259 VGNC VGNC:47561
Felis catus TMEM259 VGNC VGNC:80739
Bos taurus TMEM259 VGNC VGNC:36067