PDCD5 - programmed cell death 5 Gene

中文名称：程序性细胞死亡 5

种属: Homo sapiens

同用名: TFAR19

关于 PDCD5

功能概要

该基因编码一种在细胞凋亡过程中上调的蛋白质，在细胞凋亡过程中它会迅速从细胞质转移到细胞核。编码的蛋白质可能是 K (赖氨酸) 乙酰转移酶 5 (一种参与转录、DNA 损伤反应和细胞周期控制的蛋白质) 的重要调节因子，可抑制其蛋白酶体依赖性降解。已在 5 号和 12 号染色体上鉴定出假基因[RefSeq 提供，2010 年 12 月]

This gene encodes a protein that is upregulated during Apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010]