2. Gene
  3. MOB1B - MOB kinase activator 1B Gene

MOB1B - MOB kinase activator 1B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：MOB 激酶激活因子 1B

种属: Homo sapiens

同用名: MATS2; MOB4A; MOBKL1A

基因 ID: 92597 | 基因类型: protein coding

关于 MOB1B

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:70,901,851-70,988,168 (from NCBI)

This gene has 5 transcripts (splice variants), 216 orthologues and 6 paralogues. Ubiquitous expression in kidney (RPKM 9.7), bone marrow (RPKM 8.6) and 25 other tissues.

功能概要

该基因编码的蛋白质类似于酵母的 Mob1 蛋白质。酵母 Mob1 结合 Mps1p，这是一种对纺锤体极体复制和有丝分裂检查点调节必不可少的蛋白激酶。已发现该基因的三个转录变体编码不同的亚型。[RefSeq 提供，2011 年 9 月]

The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

MOB1B 基因产物(3)

mRNA Protein Name
NM_001244766.2 NP_001231695.1 MOB kinase activator 1B isoform 1
NM_001244767.2 NP_001231696.1 MOB kinase activator 1B isoform 3
NM_173468.4 NP_775739.1 MOB kinase activator 1B isoform 2

MOB1B 蛋白结构

Mob1_phocein

Mob1_phocein: Mob1/phocein family (30 - 205)

  • 0
  • 100
  • 200
  • 216 a.a.
蛋白主名 其他名称

MOB kinase activator 1B

MOB1 Mps One Binder homolog B

重组 MOB1B 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77449 MOB4A/MOB1B Protein, Human (His) Q7L9L4 (M1-R216) ≥95%

关联疾病

疾病名称 别名
Sveinsson Chorioretinal Atrophy

SCRA

Atrophia Areata

Helicoid Peripapillary Chorioretinal Degeneration

Hpcd

Aa

Peripapillary Chorioretinal Degeneration, Icelandic Type

Helicoidal Peripapillary Chorioretinal Degeneration

Atrophy, Chorioretinal, Sveinsson
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08574 MOB1B Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris MOB1B VGNC VGNC:43300
Macaca mulatta MOB1B VGNC VGNC:74863
Rattus norvegicus MOB1B RGD RGD:1305114
Mus musculus MOB1B MGD MGI:1915723
Felis catus MOB1B VGNC VGNC:63544
Bos taurus MOB1B VGNC VGNC:31542
Others MOB1B NCBI
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