2. Gene
  3. TM9SF2 - transmembrane 9 superfamily member 2 Gene

TM9SF2 - transmembrane 9 superfamily member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：跨膜 9 超家族成员 2

种属: Homo sapiens

同用名: P76

基因 ID: 9375 | 基因类型: protein coding

关于 TM9SF2

Cytogenetic location: 13q32.3 Genomic coordinates (GRCh38): 13:99,501,472-99,564,048 (from NCBI)

This gene has 6 transcripts (splice variants), 186 orthologues and 3 paralogues. Ubiquitous expression in thyroid (RPKM 79.3), colon (RPKM 75.9) and 25 other tissues.

功能概要

该基因编码跨膜 9 超家族的成员。编码的 76 kDa 蛋白定位于人类细胞的早期内体。编码的蛋白质具有一个保守且高度疏水的 C 端结构域，其中包含九个跨膜结构域。该蛋白质可能在小分子运输中发挥作用或充当离子通道。与该基因相关的假基因位于 X 染色体上。[RefSeq 提供，2012 年 10 月]

This gene encodes a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. The encoded protein possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. The protein may play a role in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome. [provided by RefSeq, Oct 2012]

TM9SF2 基因产物(1)

mRNA Protein Name
NM_004800.3 NP_004791.1 transmembrane 9 superfamily member 2 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ceramide metabolic process IMP
IMP: 通过突变表型推断
30660999 GOA
involved in glycosphingolipid biosynthetic process IMP
IMP: 通过突变表型推断
30660999 GOA
involved in regulation of heparan sulfate proteoglycan biosynthetic process IMP
IMP: 通过突变表型推断
28404855 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
28404855 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TM9SF2 蛋白结构

EMP70

EMP70: Endomembrane protein 70 (74 - 620)

  • 0
  • 200
  • 400
  • 600
  • 663 a.a.
蛋白主名 其他名称

transmembrane 9 superfamily member 2

76 kDa membrane protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14613 TM9SF2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21957 Tm9sf2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28474 Tm9sf2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TM9SF2 VGNC VGNC:53839
Canis familiaris TM9SF2 VGNC VGNC:47415
Rattus norvegicus TM9SF2 RGD RGD:1359230
Macaca mulatta TM9SF2 VGNC VGNC:78568
Felis catus TM9SF2 VGNC VGNC:66228
Mus musculus TM9SF2 MGD MGI:1915309
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