2. Gene
  3. Ece1 - endothelin converting enzyme 1 Gene

Ece1 - endothelin converting enzyme 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ece

基因 ID: 94204 | 基因类型: protein coding

关于 Ece1

功能概要

Enables identical protein binding activity. Involved in several processes, including positive regulation of cardiac muscle hypertrophy; positive regulation of receptor recycling; and regulation of signal transduction. Located in early endosome; external side of plasma membrane; and secretory granule. Used to study acute kidney failure; congestive heart failure; hyperhomocysteinemia; hypertension; and pulmonary hypertension. Biomarker of acute kidney failure; congestive heart failure; hypertension; nephrotic syndrome; and renal fibrosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; essential hypertension; and hypertension. Orthologous to human ECE1 (endothelin converting enzyme 1). [provided by Alliance of Genome Resources, Apr 2022]

Ece1 基因产物(1)

mRNA Protein Name
NM_053596.2 NP_446048.2 endothelin-converting enzyme 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IMP
IMP: 通过突变表型推断
8645169 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in blood vessel diameter maintenance IMP
IMP: 通过突变表型推断
22881710 RGD
involved in positive regulation of G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
15733912 RGD
involved in positive regulation of cAMP/PKA signal transduction IMP
IMP: 通过突变表型推断
22881710 RGD
involved in positive regulation of cardiac muscle hypertrophy IMP
IMP: 通过突变表型推断
20099522 RGD
involved in positive regulation of receptor recycling IMP
IMP: 通过突变表型推断
21878523 RGD
involved in protein processing IDA
IDA: 通过直接分析推断
8034569 RGD
involved in regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
21878523 RGD
involved in regulation of blood pressure IMP
IMP: 通过突变表型推断
19596829 RGD
involved in response to cadmium ion IEP
IEP: 通过表达模式推断
12189509 RGD
involved in response to hypoxia IDA
IDA: 通过直接分析推断
11813889 RGD
involved in response to muscle stretch IEP
IEP: 通过表达模式推断
16410403 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11145282 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in early endosome IDA
IDA: 通过直接分析推断
22881710 RGD
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
9449382 RGD
located in secretory granule IDA
IDA: 通过直接分析推断
11813889 RGD
located in vesicle IDA
IDA: 通过直接分析推断
9449382 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

endothelin-converting enzyme 1

ECE-1

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P3749 Mca-(ala7,lys(dnp)9)-bradykinin 99.92% 否
HY-N11772 Mutanocyclin Inhibitor 99.94% 否
HY-107762 CGS35066 Inhibitor / 否
HY-119545 PD159790 Inhibitor / 否
HY-RS04133 ECE1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-18211 CGS 35601 Inhibitor / 否
HY-RS18611 Ece1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25097 Ece1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ece1 NCBI NCBI:1889
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