1. Gene
  2. Srd5a2 - steroid 5 alpha-reductase 2 Gene

Srd5a2 - steroid 5 alpha-reductase 2 Gene

种属: Mus musculus

同用名: 5ART2; S5AR 2

基因 ID: 94224 | 基因类型: protein coding

关于 Srd5a2

功能概要

Enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Acts upstream of or within androgen biosynthetic process and male genitalia development. Predicted to be located in cell body fiber; cytoplasm; and neuronal cell body. Is expressed in genitourinary system. Human ortholog(s) of this gene implicated in hypospadias and prostate Cancer. Orthologous to human SRD5A2 (steroid 5 alpha-reductase 2). [provided by Alliance of Genome Resources, Apr 2022]

Srd5a2 基因产物(1)

mRNA Protein Name
NM_053188.3 NP_444418.1 3-oxo-5-alpha-steroid 4-dehydrogenase 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity IMP
IMP: 通过突变表型推断
11606430 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within androgen biosynthetic process IMP
IMP: 通过突变表型推断
15249131 MGI
involved in androgen biosynthetic process IMP
IMP: 通过突变表型推断
15249131 MGI
acts upstream of or within male genitalia development IMP
IMP: 通过突变表型推断
11606430 MGI
acts upstream of or within steroid biosynthetic process IMP
IMP: 通过突变表型推断
11606430 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

3-oxo-5-alpha-steroid 4-dehydrogenase 2

5 alpha-SR2

SR type 2

steroid 5 alpha reductase type2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Srd5a2 NCBI NCBI:6716