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  2. GDA - guanine deaminase Gene

GDA - guanine deaminase Gene

中文名称:鸟嘌呤脱氨酶

种属: Homo sapiens

同用名: GAH; CYPIN; GUANASE; NEDASIN

基因 ID: 9615 | 基因类型: protein coding

关于 GDA

Cytogenetic location: 9q21.13 Genomic coordinates (GRCh38): 9:72,114,608-72,259,869 (from NCBI)

This gene has 9 transcripts (splice variants) and 207 orthologues. Biased expression in small intestine (RPKM 33.5), duodenum (RPKM 32.2) and 6 other tissues.

功能概要

该基因编码一种负责鸟嘌呤水解脱氨的酶。对大鼠直系同源物的研究表明该基因在微管组装中发挥作用。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供,2011 年 11 月]

This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

GDA 基因产物(7)

mRNA Protein Name
NM_001242505.3 NP_001229434.1 guanine deaminase isoform a
NM_001242506.3 NP_001229435.1 guanine deaminase isoform c
NM_001242507.3 NP_001229436.1 guanine deaminase isoform c
NM_001351571.2 NP_001338500.1 guanine deaminase isoform d
NM_001351572.2 NP_001338501.1 guanine deaminase isoform a
NM_001351573.2 NP_001338502.1 guanine deaminase isoform e
NM_004293.5 NP_004284.1 guanine deaminase isoform b

GDA 蛋白结构

Amidohydro_1

Amidohydro_1: Amidohydrolase family (75 - 400)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 454 a.a.
蛋白主名 其他名称

guanine deaminase

cytoplasmic PSD-95 interactor

GDA 抗体

目录号 产品名 应用 反应物种
HY-P81391 GDA Antibody (YA1136) IHC-P Human

关联疾病

疾病名称 别名
Keratosis, Seborrheic

Seborrheic Keratosis

Keratosis, Seborrheic, Somatic

Basal Cell Papilloma

Keratosis Seborrheica

KERSEB

Acanthoma
Purine-Pyrimidine Metabolic Disorder

Inborn Errors Of Purine-Pyrimidine Metabolism

Disorder Of Purine Or Pyrimidine Metabolism

Hyperuricemia, Hprt-Related

Hprt-Related Gout

Kelley-Seegmiller Syndrome

Hprt Deficiency, Partial

HRH

Gout, Hprt-Related

Hprt1 Deficiency, Partial

Hrpt-Related Hyperuricemia

Hprt Deficiency, Grade I

Hprt Partial Deficiency

Hprt-Related Hyperuricemia

Hprt1 Partial Deficiency

Hypoxanthine Guanine Phosphoribosyltransferase 1 Partial Deficiency

Hypoxanthine Guanine Phosphoribosyltransferase Deficiency, Grade I

Hypoxanthine Guanine Phosphoribosyltransferase Partial Deficiency

Partial Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency

Hypoxanthine Guanine Phosphoribosyltransferase 1 Deficiency, Partial

Hyperuricemia, Hrpt-Related

Lesch-Nyhan Syndrome

Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency

LNS

Hprt Deficiency

Complete Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency

Hypoxanthine Guanine Phosphoribosyltransferase Deficiency

X-Linked Hyperuricemia

Choreoathetosis Self-Mutilation Syndrome

Hprt1 Deficiency

Hprt Deficiency, Complete

Deficiency Of Imp Pyrophosphorylase

Hgprt Deficiency

Lesch-Nyhan Disease

Hypoxanthine Guanine Phosphoribosyltransferase 1 Deficiency

Hg-Prt Deficiency

Hypoxanthine-Guanine-Phosphoribosyltransferase Deficiency

Lesch - Nyhan Syndrome

Hprt1 Disorders

Lesch Nyhan Syndrome

Complete Hprt Deficiency Complete

Lesch Nyhan Disease

Complete Hprt Deficiency

Deficiency Of Guanine Phosphoribosyltransferase

Deficiency Of Hypoxanthine Phosphoribosyltransferase

Hypoxanthine Phosphoribosyltransferase Deficiency

Juvenile Gout, Choreoathetosis, Mental Retardation Syndrome

Juvenile Hyperuricemia Syndrome

Lnd

Primary Hyperuricemia Syndrome

Total Hprt Deficiency

Total Hypoxanthine-Guanine Phosphoribosyl Transferase Deficiency

X-Linked Primary Hyperuricemia

X-Linked Uric Aciduria Enzyme Defect

Hprt Complete Deficiency

Hprt Deficiency Grade Iv

Hypoxanthine Guanine Phosphoribosyltransferase Complete Deficiency

Hypoxanthine Guanine Phosphoribosyltransferase Deficiency, Grade Iv

Hypoxanthine-Guanine Phosphoribosyltransferase 1 Deficiency

Hprt - [ Hypoxanthine-Guanine Phosphoribosyltransferase] Complete Deficiency

Total Hgprt - [Hypoxanthine-Guanine Phosphoribosyltransferase] Deficiency

Xanthinuria

Xanthine Dehydrogenase Deficiency

Xanthine Oxidase Deficiency

Hereditary Xanthinuria

Xanthic Urolithiasis

Xanthine Stone Disease

Xanthinuria, Type I

Combined Deficiency Of Xanthine Dehydrogenase And Aldehyde Oxidase

Xdh Deficiency

Classic Xanthinuria

Xanthinuria, Type Ii

Classical Xanthinuria

Xanthine Calculus

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GDA RGD RGD:621617
Felis catus GDA VGNC VGNC:62497
Mus musculus GDA MGD MGI:95678
Macaca mulatta GDA VGNC VGNC:72906
Canis familiaris GDA VGNC VGNC:41154
Bos taurus GDA VGNC VGNC:29294
Others GDA NCBI