GDA - guanine deaminase Gene

中文名称：鸟嘌呤脱氨酶

种属: Homo sapiens

同用名: GAH; CYPIN; GUANASE; NEDASIN

基因 ID: 9615 | 基因类型: protein coding

关于 GDA

Cytogenetic location: 9q21.13 Genomic coordinates (GRCh38): 9:72,114,608-72,259,869 (from NCBI)

This gene has 9 transcripts (splice variants) and 207 orthologues. Biased expression in small intestine (RPKM 33.5), duodenum (RPKM 32.2) and 6 other tissues.

功能概要

该基因编码一种负责鸟嘌呤水解脱氨的酶。对大鼠直系同源物的研究表明该基因在微管组装中发挥作用。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2011 年 11 月]

This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

GDA 基因产物(7)

mRNA	Protein	Name
NM_001242505.3	NP_001229434.1	guanine deaminase isoform a
NM_001242506.3	NP_001229435.1	guanine deaminase isoform c
NM_001242507.3	NP_001229436.1	guanine deaminase isoform c
NM_001351571.2	NP_001338500.1	guanine deaminase isoform d
NM_001351572.2	NP_001338501.1	guanine deaminase isoform a
NM_001351573.2	NP_001338502.1	guanine deaminase isoform e
NM_004293.5	NP_004284.1	guanine deaminase isoform b

GDA 蛋白结构

Amidohydro_1

0
100
200
300
400
454 a.a.

蛋白主名

其他名称

guanine deaminase

cytoplasmic PSD-95 interactor

GDA 抗体

目录号	产品名	应用	反应物种
HY-P81391	GDA Antibody (YA1136)	IHC-P	Human

关联疾病

疾病名称

别名

Keratosis, Seborrheic

Seborrheic Keratosis	Keratosis, Seborrheic, Somatic
Basal Cell Papilloma	Keratosis Seborrheica
KERSEB

Acanthoma

Purine-Pyrimidine Metabolic Disorder

Inborn Errors Of Purine-Pyrimidine Metabolism

Disorder Of Purine Or Pyrimidine Metabolism

Hyperuricemia, Hprt-Related

Hprt-Related Gout	Kelley-Seegmiller Syndrome
Hprt Deficiency, Partial	HRH
Gout, Hprt-Related	Hprt1 Deficiency, Partial
Hrpt-Related Hyperuricemia	Hprt Deficiency, Grade I
Hprt Partial Deficiency	Hprt-Related Hyperuricemia
Hprt1 Partial Deficiency	Hypoxanthine Guanine Phosphoribosyltransferase 1 Partial Deficiency
Hypoxanthine Guanine Phosphoribosyltransferase Deficiency, Grade I	Hypoxanthine Guanine Phosphoribosyltransferase Partial Deficiency
Partial Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency	Hypoxanthine Guanine Phosphoribosyltransferase 1 Deficiency, Partial
Hyperuricemia, Hrpt-Related

Lesch-Nyhan Syndrome

Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency	LNS
Hprt Deficiency	Complete Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency
Hypoxanthine Guanine Phosphoribosyltransferase Deficiency	X-Linked Hyperuricemia
Choreoathetosis Self-Mutilation Syndrome	Hprt1 Deficiency
Hprt Deficiency, Complete	Deficiency Of Imp Pyrophosphorylase
Hgprt Deficiency	Lesch-Nyhan Disease
Hypoxanthine Guanine Phosphoribosyltransferase 1 Deficiency	Hg-Prt Deficiency
Hypoxanthine-Guanine-Phosphoribosyltransferase Deficiency	Lesch - Nyhan Syndrome
Hprt1 Disorders	Lesch Nyhan Syndrome
Complete Hprt Deficiency Complete	Lesch Nyhan Disease
Complete Hprt Deficiency	Deficiency Of Guanine Phosphoribosyltransferase
Deficiency Of Hypoxanthine Phosphoribosyltransferase	Hypoxanthine Phosphoribosyltransferase Deficiency
Juvenile Gout, Choreoathetosis, Mental Retardation Syndrome	Juvenile Hyperuricemia Syndrome
Lnd	Primary Hyperuricemia Syndrome
Total Hprt Deficiency	Total Hypoxanthine-Guanine Phosphoribosyl Transferase Deficiency
X-Linked Primary Hyperuricemia	X-Linked Uric Aciduria Enzyme Defect
Hprt Complete Deficiency	Hprt Deficiency Grade Iv
Hypoxanthine Guanine Phosphoribosyltransferase Complete Deficiency	Hypoxanthine Guanine Phosphoribosyltransferase Deficiency, Grade Iv
Hypoxanthine-Guanine Phosphoribosyltransferase 1 Deficiency	Hprt - [ Hypoxanthine-Guanine Phosphoribosyltransferase] Complete Deficiency
Total Hgprt - [Hypoxanthine-Guanine Phosphoribosyltransferase] Deficiency

Xanthinuria

Xanthine Dehydrogenase Deficiency	Xanthine Oxidase Deficiency
Hereditary Xanthinuria	Xanthic Urolithiasis
Xanthine Stone Disease	Xanthinuria, Type I
Combined Deficiency Of Xanthine Dehydrogenase And Aldehyde Oxidase	Xdh Deficiency
Classic Xanthinuria	Xanthinuria, Type Ii
Classical Xanthinuria	Xanthine Calculus

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-145269	AL-GDa62	Inhibitor	/	否
HY-RS05345	GDA Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS09965	PAEP Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS13096	SLC25A16 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS18216	Gda Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS24693	Gda Rat Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	GDA	RGD	RGD:621617
Felis catus	GDA	VGNC	VGNC:62497
Mus musculus	GDA	MGD	MGI:95678
Macaca mulatta	GDA	VGNC	VGNC:72906
Canis familiaris	GDA	VGNC	VGNC:41154
Bos taurus	GDA	VGNC	VGNC:29294
Others	GDA	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

GDA - guanine deaminase Gene

关于 GDA

功能概要

GDA 基因产物(7)

GDA 蛋白结构

GDA 抗体

关联疾病

直系同源

热门区域

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GDA - guanine deaminase Gene

关于 GDA

功能概要

GDA 基因产物(7)

GDA 蛋白结构

GDA 抗体

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z