2. Gene
  3. USP6NL - USP6 N-terminal like Gene

USP6NL - USP6 N-terminal like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：USP6 N 端类似

种属: Homo sapiens

同用名: RNTRE; TRE2NL; USP6NL-IT1

基因 ID: 9712 | 基因类型: protein coding

关于 USP6NL

Cytogenetic location: 10p14 Genomic coordinates (GRCh38): 10:11,460,510-11,611,650 (from NCBI)

This gene has 6 transcripts (splice variants), 217 orthologues and 45 paralogues. Broad expression in testis (RPKM 11.0), esophagus (RPKM 10.8) and 24 other tissues.

功能概要

启用 GTPase 激活剂活性和小 GTPase 结合活性。参与多个过程，包括质膜到核内体的运输； GTP 酶活性的正调节；和逆行运输，质膜到高尔基体。位于细胞质囊泡和质膜中。 [由基因组资源联盟提供，2022 年 4 月]

Enables GTPase activator activity and small GTPase binding activity. Involved in several processes, including plasma membrane to endosome transport; positive regulation of GTPase activity; and retrograde transport, plasma membrane to Golgi. Located in cytoplasmic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

USP6NL 基因产物(5)

mRNA Protein Name
NM_001080491.5 NP_001073960.1 USP6 N-terminal-like protein isoform 2
NM_001391959.1 NP_001378888.1 USP6 N-terminal-like protein isoform 3
NM_001391960.1 NP_001378889.1 USP6 N-terminal-like protein isoform 4
NM_001391961.1 NP_001378890.1 USP6 N-terminal-like protein isoform 5
NM_014688.5 NP_055503.1 USP6 N-terminal-like protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase activator activity IDA
IDA: 通过直接分析推断
17562788 GOA
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
17562788 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Golgi organization IMP
IMP: 通过突变表型推断
17684057 GOA
involved in plasma membrane to endosome transport IMP
IMP: 通过突变表型推断
17562788 GOA
involved in positive regulation of GTPase activity IDA
IDA: 通过直接分析推断
17562788 GOA
involved in regulation of Golgi organization IMP
IMP: 通过突变表型推断
17562788 GOA
NOT involved in regulation of cilium assembly IMP
IMP: 通过突变表型推断
17646400 GOA
involved in retrograde transport, plasma membrane to Golgi IMP
IMP: 通过突变表型推断
17684057 GOA
involved in virion assembly IMP
IMP: 通过突变表型推断
21680502 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
17684057 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
17562788 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

USP6NL 蛋白结构

RabGAP-TBC

RabGAP-TBC: Rab-GTPase-TBC domain (104 - 312)

  • 0
  • 200
  • 400
  • 600
  • 828 a.a.
蛋白主名 其他名称

USP6 N-terminal-like protein

related to the N-terminus of tre

关联疾病

疾病名称 别名
Nipah Virus Encephalitis

Equine Morbillivirus
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15567 USP6NL Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20616 Usp6nl Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS27124 Usp6nl Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris USP6NL VGNC VGNC:48204
Macaca mulatta USP6NL VGNC VGNC:79055
Rattus norvegicus USP6NL RGD RGD:1311786
Bos taurus USP6NL VGNC VGNC:36737
Mus musculus USP6NL MGD MGI:2138893
Felis catus USP6NL VGNC VGNC:66897
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