2. Gene
  3. Hadha - hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha Gene

Hadha - hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mtpa; TP-alpha

基因 ID: 97212 | 基因类型: protein coding

关于 Hadha

功能概要

Enables long-chain-3-hydroxyacyl-CoA dehydrogenase activity. Acts upstream of or within fatty acid beta-oxidation and response to Insulin. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in fatty liver disease and mitochondrial trifunctional protein deficiency. Orthologous to human HADHA (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Hadha 基因产物(1)

mRNA Protein Name
NM_178878.3 NP_849209.1 trifunctional enzyme subunit alpha, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables long-chain-3-hydroxyacyl-CoA dehydrogenase activity IDA
IDA: 通过直接分析推断
15240869 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
29949755 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within fatty acid beta-oxidation IMP
IMP: 通过突变表型推断
11390422 MGI
acts upstream of or within response to insulin IMP
IMP: 通过突变表型推断
15887119 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

trifunctional enzyme subunit alpha, mitochondrial

hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit

monolysocardiolipin acyltransferase

相关产品

Approval
生物活性分子 (3)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0968A Trimetazidine Inducer 99.84% 是
HY-B0968 Trimetazidine dihydrochloride Inducer 99.91% 是
HY-B0968R Trimetazidine dihydrochloride (Standard) Inducer 99.94% 否
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-B0968S Trimetazidine-d8 dihydrochloride Inducer 99.87% 否
HY-RS05990 HADHA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-B0968S1 Trimetazidine-d9 dihydrochloride Inducer / 否
HY-RS17506 Hadha Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23963 Hadha Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hadha NCBI NCBI:3030
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