2. Gene
  3. Mael - maelstrom spermatogenic transposon silencer Gene

Mael - maelstrom spermatogenic transposon silencer Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 4933405K18Rik

基因 ID: 98558 | 基因类型: protein coding

关于 Mael

功能概要

Predicted to enable sequence-specific DNA binding activity. Involved in DNA methylation involved in gamete generation; gene silencing by RNA; and piRNA metabolic process. Acts upstream of or within several processes, including intrinsic apoptotic signaling pathway in response to DNA damage; male gamete generation; and negative regulation of macromolecule metabolic process. Located in several cellular components, including chromosome; cytoplasmic ribonucleoprotein granule; and perinuclear region of cytoplasm. Is expressed in brain; early conceptus; and genitourinary system. Orthologous to human MAEL (maelstrom spermatogenic transposon silencer). [provided by Alliance of Genome Resources, Apr 2022]

Mael 基因产物(1)

mRNA Protein Name
NM_175296.4 NP_780505.1 protein maelstrom homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16787967 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within DNA damage response IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of apoptotic process IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of or within cell morphogenesis IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of ectopic germ cell programmed cell death IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of or within fertilization IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of gene expression IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of or within homologous chromosome pairing at meiosis IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of or within male meiotic nuclear division IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of or within negative regulation of developmental process IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of or within negative regulation of gene expression IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of or within negative regulation of reproductive process IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
18694567 MGI
involved in piRNA processing IMP
IMP: 通过突变表型推断
18694567 MGI
acts upstream of or within regulation of organ growth IMP
IMP: 通过突变表型推断
18694567 MGI
involved in regulatory ncRNA-mediated gene silencing IMP
IMP: 通过突变表型推断
18694567 MGI
involved in retrotransposon silencing by piRNA-directed DNA methylation IMP
IMP: 通过突变表型推断
20011505 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
18694567 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in P granule IDA
IDA: 通过直接分析推断
16787967 MGI
NOT located in XY body IDA
IDA: 通过直接分析推断
18694567 MGI
located in XY body IDA
IDA: 通过直接分析推断
16787967 MGI
located in autosome IDA
IDA: 通过直接分析推断
16787967 MGI
located in chromatin IDA
IDA: 通过直接分析推断
16787967 MGI
located in chromatoid body IDA
IDA: 通过直接分析推断
16787967 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
16787967 MGI
located in male germ cell nucleus IDA
IDA: 通过直接分析推断
16787967 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
18694567 MGI
located in piP-body IDA
IDA: 通过直接分析推断
20011505 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein maelstrom homolog

maelstrom homolog

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07955 MAEL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21370 Mael Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27889 Mael Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mael NCBI NCBI:84944
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