2. Gene
  3. TRIM66 - tripartite motif containing 66 Gene

TRIM66 - tripartite motif containing 66 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含三方基序 66

种属: Homo sapiens

同用名: TIF1D; C11orf29; TIF1DELTA

基因 ID: 9866 | 基因类型: protein coding

关于 TRIM66

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:8,612,040-8,683,231 (from NCBI)

This gene has 13 transcripts (splice variants), 185 orthologues and 80 paralogues. Broad expression in testis (RPKM 4.5), skin (RPKM 3.3) and 25 other tissues.

功能概要

预测启用染色质结合活性和相同的蛋白质结合活性。预计在转录的负调节上游或负调节内起作用，以 DNA 为模板。位于侵略体和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable chromatin binding activity and identical protein binding activity. Predicted to act upstream of or within negative regulation of transcription, DNA-templated. Located in aggresome and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TRIM66 基因产物(4)

mRNA Protein Name
NM_001388022.1 NP_001374951.1 tripartite motif-containing protein 66 isoform 2
NM_001388023.1 NP_001374952.1 tripartite motif-containing protein 66 isoform 3
NM_001388024.1 NP_001374953.1 tripartite motif-containing protein 66 isoform 4
NM_014818.2 NP_055633.1 tripartite motif-containing protein 66 isoform 1
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
25593309 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TRIM66 蛋白结构

zf-B_box

zf-B_box: B-box zinc finger (64 - 99)

PHD

PHD: PHD-finger (972 - 1016)

Bromodomain

Bromodomain: Bromodomain (1050 - 1132)

  • 0
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  • 1000
  • 1216 a.a.
蛋白主名 其他名称

tripartite motif-containing protein 66

transcriptional intermediary factor 1 delta

关联疾病

疾病名称 别名
Brain Oligodendroglioma

Oligodendroglioma Of Brain
Non-Invasive Bladder Urothelial Carcinoma

Stage 0 Bladder Urothelial Carcinoma
Cystathioninuria

Cystathionase Deficiency

Gamma-Cystathionase Deficiency

Cystathione Gamma-Lyase Deficiency Syndrome

Cystathionine Gamma-Lyase Deficiency Syndrome

CSTNU
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15066 TRIM66 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus TRIM66 VGNC VGNC:66549
Macaca mulatta TRIM66 VGNC VGNC:79766
Mus musculus TRIM66 MGD MGI:2152406
Bos taurus TRIM66 VGNC VGNC:36348
Rattus norvegicus TRIM66 RGD RGD:1595847
Canis familiaris TRIM66 VGNC VGNC:47833
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