2. Gene
  3. Atp1a2 - ATPase, Na+/K+ transporting, alpha 2 polypeptide Gene

Atp1a2 - ATPase, Na+/K+ transporting, alpha 2 polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Atpa-3; mKIAA0778

基因 ID: 98660 | 基因类型: protein coding

关于 Atp1a2

功能概要

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and alkali metal ion binding activity. Involved in several processes, including cellular response to steroid hormone stimulus; locomotory exploration behavior; and response to auditory stimulus. Acts upstream of or within several processes, including forebrain development; regulation of blood circulation; and regulation of muscle contraction. Located in T-tubule; cell projection; and neuronal cell body. Is expressed in several structures, including genitourinary system; heart; musculature; nervous system; and sensory organ. Used to study familial hemiplegic migraine 2. Human ortholog(s) of this gene implicated in alternating hemiplegia of childhood; benign neonatal seizures; familial hemiplegic migraine 2; hypertension; and migraine with aura. Orthologous to human ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Atp1a2 基因产物(1)

mRNA Protein Name
NM_178405.3 NP_848492.1 sodium/potassium-transporting ATPase subunit alpha-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15485817 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within L-ascorbic acid metabolic process IGI
IGI: 通过遗传相互作用推断
33544780 MGI
acts upstream of or within adult locomotory behavior IMP
IMP: 通过突变表型推断
17234593 MGI
acts upstream of or within amygdala development IMP
IMP: 通过突变表型推断
12805306 MGI
acts upstream of or within behavioral fear response IMP
IMP: 通过突变表型推断
12805306 MGI
acts upstream of or within blood circulation IGI
IGI: 通过遗传相互作用推断
33544780 MGI
involved in cellular response to steroid hormone stimulus IDA
IDA: 通过直接分析推断
16243970 MGI
acts upstream of or within fear response IMP
IMP: 通过突变表型推断
21731499 MGI
acts upstream of or within locomotion IMP
IMP: 通过突变表型推断
12458206 MGI
involved in locomotory exploration behavior IMP
IMP: 通过突变表型推断
20936682 MGI
acts upstream of or within membrane depolarization IMP
IMP: 通过突变表型推断
30819023 MGI
acts upstream of or within negative regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
10360172 MGI
acts upstream of or within negative regulation of heart contraction IMP
IMP: 通过突变表型推断
10360172 MGI
acts upstream of or within negative regulation of striated muscle contraction IMP
IMP: 通过突变表型推断
11507009 MGI
acts upstream of or within neuronal action potential propagation IMP
IMP: 通过突变表型推断
21731499 MGI
acts upstream of or within neurotransmitter uptake IMP
IMP: 通过突变表型推断
12805306 MGI
involved in neurotransmitter uptake IMP
IMP: 通过突变表型推断
12805306 MGI
acts upstream of or within olfactory cortex development IMP
IMP: 通过突变表型推断
12805306 MGI
acts upstream of or within regulation of blood pressure IGI
IGI: 通过遗传相互作用推断
16243970 MGI
acts upstream of or within regulation of muscle contraction IMP
IMP: 通过突变表型推断
10360172 MGI
acts upstream of or within regulation of respiratory gaseous exchange by nervous system process IMP
IMP: 通过突变表型推断
12458206 MGI
acts upstream of or within regulation of smooth muscle contraction IMP
IMP: 通过突变表型推断
14627611 MGI
acts upstream of or within regulation of striated muscle contraction IMP
IMP: 通过突变表型推断
15253893 MGI
acts upstream of or within regulation of the force of heart contraction IMP
IMP: 通过突变表型推断
10360172 MGI
acts upstream of or within regulation of vasoconstriction IGI
IGI: 通过遗传相互作用推断
14627611 MGI
acts upstream of or within regulation of vasoconstriction IMP
IMP: 通过突变表型推断
14627611 MGI
involved in response to auditory stimulus IMP
IMP: 通过突变表型推断
20936682 MGI
involved in response to glycoside IMP
IMP: 通过突变表型推断
16243970 MGI
acts upstream of or within response to potassium ion IMP
IMP: 通过突变表型推断
30819023 MGI
acts upstream of or within visual learning IMP
IMP: 通过突变表型推断
17234593 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in T-tubule IDA
IDA: 通过直接分析推断
16292983 MGI
located in cell projection IDA
IDA: 通过直接分析推断
12458206 MGI
is active in cell surface IDA
IDA: 通过直接分析推断
17804407 MGI
is active in endoplasmic reticulum IDA
IDA: 通过直接分析推断
21731499 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
12458206 MGI
is active in plasma membrane IDA
IDA: 通过直接分析推断
21731499 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
17804407 MGI
located in sarcolemma IDA
IDA: 通过直接分析推断
15485817 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sodium/potassium-transporting ATPase subunit alpha-2

Na(+)/K(+) ATPase alpha(+) subunit

Na(+)/K(+) ATPase alpha-2 subunit

sodium pump subunit alpha-2

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01183 ATP1A2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS01187 ATP1B2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21822 Atp1a2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21823 Atp1b2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28339 Atp1a2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atp1a2 NCBI NCBI:477
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