2. Gene
  3. Sall4 - spalt like transcription factor 4 Gene

Sall4 - spalt like transcription factor 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tex20; 5730441M18Rik; C330011P20Rik

基因 ID: 99377 | 基因类型: protein coding

关于 Sall4

功能概要

This gene belongs to the spalt family of zinc finger transcription factors. In mouse, functions for this gene have been described in many embryonic developmental processes, including brain, heart, and limb development. In addition, this gene is an important pluripotency factor that is required for stem cell maintenance. Homozygous mutant mice display embryonic lethality, while conditional knock-out in embryonic germ cells results in failure to establish a robust stem cell population. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Sall4 基因产物(3)

mRNA Protein Name
NM_175303.4 NP_780512.2 sal-like protein 4 isoform a
NM_201395.3 NP_958797.2 sal-like protein 4 isoform b
NM_201396.3 NP_958798.2 sal-like protein 4 isoform c
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16380715 MGI
enables transcription factor binding IPI
IPI: 通过物理相互作用推断
26523946 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within embryonic limb morphogenesis IGI
IGI: 通过遗传相互作用推断
16380715 MGI
acts upstream of or within embryonic limb morphogenesis IMP
IMP: 通过突变表型推断
16380715 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
16380715 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
17060609 MGI
acts upstream of or within inner cell mass cell proliferation IMP
IMP: 通过突变表型推断
16790473 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16380715 MGI
acts upstream of or within neural tube closure IGI
IGI: 通过遗传相互作用推断
16790473 MGI
acts upstream of or within neural tube closure IMP
IMP: 通过突变表型推断
16790473 MGI
acts upstream of or within neural tube development IGI
IGI: 通过遗传相互作用推断
18818376 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16380715 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16380715 MGI
acts upstream of or within somatic stem cell population maintenance IMP
IMP: 通过突变表型推断
20720539 MGI
acts upstream of or within tissue development IMP
IMP: 通过突变表型推断
17060609 MGI
acts upstream of or within ventricular septum development IGI
IGI: 通过遗传相互作用推断
16790473 MGI
acts upstream of or within ventricular septum development IMP
IMP: 通过突变表型推断
16790473 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in heterochromatin IDA
IDA: 通过直接分析推断
17295837 MGI
located in nucleus IDA
IDA: 通过直接分析推断
19796622 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
19796622 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sal-like protein 4

sal-like 4

zinc finger protein SALL4

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-144998 NVP-DKY709 Inhibitor 99.66% 否
HY-169348 β-catenin-IN-8 Inhibitor / 否
HY-RS12420 SALL4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W1128213 IKZF2-degrader 2 Degrader / 否
HY-W599279 ABS-752 Degrader / 否
HY-RS21750 Sall4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28268 Sall4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sall4 NCBI NCBI:57167
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