2. Gene
  3. Dpyd - dihydropyrimidine dehydrogenase Gene

Dpyd - dihydropyrimidine dehydrogenase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: DPD; DHPDHase; E330028L06Rik

基因 ID: 99586 | 基因类型: protein coding

关于 Dpyd

功能概要

Enables dihydropyrimidine dehydrogenase (NADP+) activity. Involved in pyrimidine nucleoside monophosphate catabolic process. Acts upstream of or within pyrimidine nucleobase catabolic process. Is active in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculature; and sensory organ. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; dihydropyrimidine dehydrogenase deficiency; and pancreatic Cancer. Orthologous to human DPYD (dihydropyrimidine dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Dpyd 基因产物(1)

mRNA Protein Name
NM_170778.3 NP_740748.1 dihydropyrimidine dehydrogenase [NADP(+)]
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables dihydropyrimidine dehydrogenase (NADP+) activity IDA
IDA: 通过直接分析推断
5472365 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in CMP catabolic process IDA
IDA: 通过直接分析推断
5472365 MGI
involved in UMP catabolic process IDA
IDA: 通过直接分析推断
5472365 MGI
involved in dCMP catabolic process IDA
IDA: 通过直接分析推断
5472365 MGI
involved in dUMP catabolic process IDA
IDA: 通过直接分析推断
5472365 MGI
acts upstream of or within pyrimidine nucleobase catabolic process IDA
IDA: 通过直接分析推断
12651209 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytosol IDA
IDA: 通过直接分析推断
5472365 MGI
located in cytosol IDA
IDA: 通过直接分析推断
12651209 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dihydropyrimidine dehydrogenase [NADP(+)]

dihydrothymine dehydrogenase

dihydrouracil dehydrogenase

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-17469 Gimeracil Inhibitor 99.72% 否
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03979 DPYD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W777340 Gimeracil-13C3 / 否
HY-17469S Gimeracil-13C3,15N / 否
HY-RS21328 Dpyd Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27847 Dpyd Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dpyd NCBI NCBI:1806
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