2. Gene
  3. SLC23A2 - solute carrier family 23 member 2 Gene

SLC23A2 - solute carrier family 23 member 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 23 成员 2

种属: Homo sapiens

同用名: NBTL1; SVCT2; YSPL2; SLC23A1

基因 ID: 9962 | 基因类型: protein coding

关于 SLC23A2

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:4,852,358-5,010,313 (from NCBI)

This gene has 5 transcripts (splice variants), 211 orthologues and 2 paralogues. Broad expression in adrenal (RPKM 40.7), brain (RPKM 20.8) and 23 other tissues.

功能概要

维生素 C 被人体吸收并分布到器官需要两种钠依赖性维生素 C 转运蛋白。该基因编码两种必需的转运蛋白之一，编码的蛋白质负责维生素 C 的组织特异性摄取。此前，该基因的官方符号为 SLC23A1。[RefSeq 提供，2008 年 7 月]

The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters and the encoded protein accounts for tissue-specific uptake of vitamin C. Previously, this gene had an official symbol of SLC23A1. [provided by RefSeq, Jul 2008]

SLC23A2 基因产物(2)

mRNA Protein Name
NM_005116.6 NP_005107.4 solute carrier family 23 member 2
NM_203327.2 NP_976072.1 solute carrier family 23 member 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-ascorbate:sodium symporter activity IDA
IDA: 通过直接分析推断
10471399 GOA
enables L-ascorbic acid transmembrane transporter activity IDA
IDA: 通过直接分析推断
10471399 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
34673103 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in L-ascorbic acid transmembrane transport IDA
IDA: 通过直接分析推断
10471399 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
18417304 GOA
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
15993839 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
10631088 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

solute carrier family 23 member 2

Na(+)/L-ascorbic acid transporter 2

关联疾病

疾病名称 别名
Hypoascorbemia

Scurvy

Ascorbic Acid Deficiency

Vitamin C Deficiency

Vitamin C, Inability To Synthesize

Deficiency Of Vitamin C

Scorbutus

Vitamin C
Micronodular Basal Cell Carcinoma

Skin Micronodular Basal Cell Carcinoma

Basal Cell Carcinoma, Micronodular
Hemophagocytic Lymphohistiocytosis, Familial, 2

Familial Hemophagocytic Lymphohistiocytosis 2

FHL2

Hplh2

Hlh2

Hemophagocytic Lymphohistiocytosis, Familial, 2, Susceptibility To

Lymphohistiocytosis, Hemophagocytic, Familial, Type 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13081 SLC23A1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS13082 SLC23A2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta SLC23A2 VGNC VGNC:98446
Rattus norvegicus SLC23A2 RGD RGD:619876
Felis catus SLC23A2 VGNC VGNC:65248
Canis familiaris SLC23A2 VGNC VGNC:46283
Mus musculus SLC23A2 MGD MGI:1859682
Bos taurus SLC23A2 VGNC VGNC:34734
Others SLC23A2 NCBI
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