2. Academic Validation
  3. Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae

Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae

  • Antimicrob Agents Chemother. 2002 Sep;46(9):3094-5. doi: 10.1128/AAC.46.9.3094-3095.2002.
Sue E Baum 1,  Sharon A Crawford,  M L McElmeel,  Cynthia G Whitney,  James H Jorgensen
Affiliations

Affiliation

  • 1 Infectious Disease Service of Brooke Army Medical Center, San Antonio, Texas, USA.
PMID: 12183281 DOI: 10.1128/AAC.46.9.3094-3095.2002
Abstract

The activity of AZD2563 against 250 highly resistant pneumococci and 267 drug-susceptible isolates was determined. The AZD2563 MICs for 50 and 90% of the strains tested were 1 and 2 micro g/ml and 0.5 and 1 micro g/ml, respectively, for the two isolate groups. These MICs were within 1 log(2) dilution of those of linezolid.

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