2. Academic Validation
  3. Ceftaroline fosamil, a cephalosporin derivative for the potential treatment of MRSA infection

Ceftaroline fosamil, a cephalosporin derivative for the potential treatment of MRSA infection

  • Curr Opin Investig Drugs. 2008 Feb;9(2):201-9.
Daniel Parish 1,  Noah Scheinfeld
Affiliations

Affiliation

  • 1 Columbia University School of Medicine, 1090 Amsterdam Avenue, St Lukes Roosevelt Hospital Center, New York, NY 10025, USA.
PMID: 18246523
Abstract

Forest Laboratories (following its acquisition of Cerexa Inc, a spin-out from Peninsula Pharmaceuticals Inc), under license from Takeda, is developing ceftaroline fosamil, an N-phosphono prodrug of ceftaroline, a derivative of a fourth-generation cephalosporin, for the potential treatment of methicillin-resistant Staphylococcus aureus Infection. Phase III clinical trials evaluating ceftaroline fosamil for community acquired pneumonia and complicated skin and skin structure infections are underway.

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