2. Academic Validation
  3. Influenza neuraminidase

Influenza neuraminidase

  • Influenza Other Respir Viruses. 2012 Jul;6(4):245-56. doi: 10.1111/j.1750-2659.2011.00304.x.
Gillian M Air 1
Affiliations

Affiliation

  • 1 Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. Gillian-air@ouhsc.edu
PMID: 22085243 DOI: 10.1111/j.1750-2659.2011.00304.x
Abstract

Influenza neuraminidase is the target of two licensed antivirals that have been very successful, with several more in development. However, neuraminidase has been largely ignored as a vaccine target despite evidence that inclusion of neuraminidase in the subunit vaccine gives increased protection. This article describes current knowledge on the structure, enzyme activity, and antigenic significance of neuraminidase.

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