2. Academic Validation
  3. Chemical constituents of Brazilian Propolis from the state of Bahia and their growth inhibitory activities against cancer cells

Chemical constituents of Brazilian Propolis from the state of Bahia and their growth inhibitory activities against cancer cells

  • Biosci Biotechnol Biochem. 2018 Mar;82(3):417-421. doi: 10.1080/09168451.2018.1427550.
Taichi Mitsui 1,  Sho Hotta 1,  Shigemi Tazawa 1,  Yasuko Arai 1,  Kenji Kato 1,  Kenji Ichihara 1
Affiliations

Affiliation

  • 1 a Nagaragawa Research Center, Api Co. Ltd. , Gifu , Japan.
PMID: 29370717 DOI: 10.1080/09168451.2018.1427550
Abstract

A novel 2-phenoxychromone (1) and five known Flavones (2-6) were isolated from northeastern Brazilian propolis in the state of Bahia. The chemical structures of these six compounds were determined by spectroscopic investigations and single-crystal X-ray analysis. The isolated compounds showed growth-inhibitory activities, in varying degrees, against human tumor cell lines. This is the first report on the discovery of a novel 2-phenoxychromone from propolis.

Keywords

2-Phenoxychromone; Bahia state; Brazilian propolis; anti-cancer.

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