1. Academic Validation
  2. Two new naphthalene glycosides from the seeds of Cassia obtusifolia

Two new naphthalene glycosides from the seeds of Cassia obtusifolia

  • J Asian Nat Prod Res. 2019 Oct;21(10):970-976. doi: 10.1080/10286020.2018.1478816.
Xu Pang 1 2 Na-Na Li 1 He-Shui Yu 1 Li-Ping Kang 3 Hai-Yang Yu 1 2 Xin-Bo Song 1 Guan-Wei Fan 4 Li-Feng Han 1 2
Affiliations

Affiliations

  • 1 Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin 300193 , China.
  • 2 Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin 300193 , China.
  • 3 State Key Laboratory of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences , Beijing 100700 , China.
  • 4 Central Laboratory, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine , Tianjin 300193 , China.
Abstract

A phytochemical study on the seeds of Cassia obtusifolia was carried out, which finally led to obtain two naphthalenes (1 and 2), two naphthopyrans (3 and 4) and twelve Anthraquinones (5-16). The structures of all compounds were established mainly by NMR and MS experiments as well as the necessary chemical evidence. Among them, 1 and 2 (obtusinaphthalensides A and B) were identified to be new naphthalene glycosides.

Keywords

Legumenosae; Semen Cassiae; naphthalene; obtusinaphthalenside.

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