2. Academic Validation
  3. Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones

Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones

  • J Nat Prod. 1979 Jan-Feb;42(1):85-91. doi: 10.1021/np50001a002.
J M Edwards,  R F Raffauf,  P W Le Quesne
PMID: 469554 DOI: 10.1021/np50001a002
Abstract

Several hundred flavonoid derivatives, natural and synthetic, which have been tested in the screening program of the National Cancer Institute, have been examined for indications of structure-activity relationships which might exist among these compounds. No such relationships are apparent. In spite of occasional activity these compounds do not warrant further detailed pursuit as anti-tumor agents.

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