2. Academic Validation
  3. Hydroxymycotrienins A and B, new ansamycin group antibiotics

Hydroxymycotrienins A and B, new ansamycin group antibiotics

  • J Antibiot (Tokyo). 1996 May;49(5):425-31. doi: 10.7164/antibiotics.49.425.
N Hosokawa 1,  H Naganawa,  M Hamada,  T Takeuchi,  S Ikeno,  M Hori
Affiliations

Affiliation

  • 1 Institute of Microbial Chemistry, Tokyo, Japan.
PMID: 8682718 DOI: 10.7164/antibiotics.49.425
Abstract

New ansamycins designated hydroxymycotrienins A and B were isolated from culture broths of Bacillus sp. BMJ958-62F4. The two Antibiotics inhibited more strongly the growth of human cervical Cancer cell lines of human papilloma virus (HPV) positive than that of HPV negative cell lines. The structures, some biological and biochemical properties are reported.

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