1. 一站式药筛
  2. 化合物库
  3. 胺类片段化合物库
胺类片段化合物库 - Amine Fragment Library

Cat. No.: HY-L236

基于片段的药物发现 (FBDD) 可根据片段分子的基团来进一步划分,这具有战略上的优势,这一特性使得成果能够被进一步优化,并为通过组合多个片段来合理设计更大分子提供了可能性。目前许多上市药物,如 Galatamine、Tacrine、和 Rivastigmine,均为胺类化合物。胺类结构对药物的疗效有着显著的贡献,这种基团有助于提高药物的溶解度、改善生物利用度,并确保药物在保质期内的稳定性,这对于开发有效的药物至关重要。

MCE 可以提供 0 种胺类片段化合物,这些化合物均符合类药 “3原则 (RO3)”,即分子量 ≤300 Da,氢供体 (H-donors) ≤3,氢受体 (H-acceptors) ≤3,cLogP ≤3。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
- +

Compound Screening Libraries

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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情

活性描述 & 特点

Biological Activity

•   A unique collection of 0 amine fragment compounds for fragment-based drug discovery (FBDD).

•   The fragemnts follow the Rule of Three.

•   A useful tool for the fragment-based approach to drug discovery (FBDD).

•   More detailed compound information with structure, Molecular Weight, cLogP, H-donor and H-acceptor number.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 0 amine fragment compounds supplied as pre-dissolved Solutions or Solid

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal

Storage:

-80°C

Shipping:

Blue ice or dry ice

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  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式(固体或溶液)
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    Amine Fragment Library
    目录号:
    HY-L236
    需求量: