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Calcium Ion Channel Library

Cat. No.: HY-L0098V

Calcium Ion Channel Library contains about 10,560 compounds, and designed for discovery of new Voltage-gated calcium channel blockers. Calcium ion channels are responsible for an unusually large variety of physiological functions. Calcium ions entering the cell through voltage-gated channels serve as the second messenger of electrical signaling, initiating many different cellular events. Calcium Ion Channel Library encompasses both known chemotypes and molecules based on novel scaffolds identified in their in silico studies and MedChem based scaffold hopping projects.
  • Chinese National Compound Library
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Biological activity

•   86% compounds in the library are lead-likeness, the average Fsp3 is 0.38, the average TPSA is 60.5 Å2.

•   Privileged chemotypes, such as dihydropyridines, GABA-analogues, succinimides, 4-substituted prolines, and quinazolines.

•   Unique analogues of piperazine and 4-aminopiperidine.

•   Drug like compounds with novel chemotypes, the most attractive structural and physical chemical properties.

•   Databases and compounds are provided by Enamine.

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  • Chinese National Compound Library
  • Chinese National Compound Library

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Calcium Ion Channel Library
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