1. Cell Cycle/DNA Damage
  2. CDK
  3. (2S,3R)-Voruciclib

(2S,3R)-Voruciclib 

目录号: HY-12422C
产品使用指南

(2S,3R)-Voruciclib 是 Voruciclib 的 (2S,3R)-对映异构体。(2S,3R)-Voruciclib 是一种具有口服活性的 CDK 抑制剂。

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(2S,3R)-Voruciclib Chemical Structure

(2S,3R)-Voruciclib Chemical Structure

CAS No. : 1253731-24-6

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Description

(2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. (2S,3R)-Voruciclib is an orally active CDK inhibitor[1].

IC50 & Target

CDK[1]

In Vitro

(2S,3R)-Voruciclib (Compound B, formula I) is used in combination with a compound capable of inhibiting EGFR kinase activity and Gemcitabine to treat pancreatic cancer[1].

Molecular Weight

469.84

Formula

C₂₂H₁₉ClF₃NO₅

CAS No.

1253731-24-6

SMILES

ClC1=CC(C(F)(F)F)=CC=C1C(OC2=C(C(O)=CC(O)=C23)[C@H]([C@H]4CO)CCN4C)=CC3=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

(2S,3R)-VoruciclibCDKCyclin dependent kinase(2S,3R)-enantiomerVoruciclibpancreaticcancerInhibitorinhibitorinhibit

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产品名称:
(2S,3R)-Voruciclib
目录号:
HY-12422C
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